Rosuvastatin Tablet 10mg (Rosuvastatin Calcium)

Adult dosage

For adult patients with primary hypercholesterolemia, treatment can be administered once daily at any time, regardless of meals. The initial dose is 5mg once daily, while the maintenance dose is generally 10mg once daily for most patients. The maintenance dose should be adjusted appropriately based on LDL-cholesterol levels, treatment goals, and patient response, with at least 4 weeks or more intervals between adjustments, and can be increased to a maximum of 20mg per day.

Children's dosage

In pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years), the dosage ranges from 5mg to 20mg once daily, doses are adjusted according to individual treatment goals. Adjust dosage

This medication should not be used in individuals who are allergic to any of the components. It should not be administered to patients with active liver disease or unexplained elevated liver enzyme levels. Patients with muscle disease or severe renal impairment should also avoid taking this medication. It should not be given to pregnant or breastfeeding women, or to women of childbearing potential who are not using effective contraception. Patients at high risk of muscle disease, such as those with moderate to severe renal impairment or hypothyroidism, should avoid high doses of this medication. Patients with genetic metabolic disorders such as lactose intolerance should not take this medication. This medication should be used with caution in individuals with a history of liver disease or those who consume excessive alcohol, and regular liver function tests are required. If symptoms of muscle pain or weakness occur, medical attention should be sought immediately for necessary testing. Individuals with reduced renal function or conditions such as hypothyroidism are at a greater risk of muscular adverse reactions, hence careful monitoring is necessary. This medication can rarely cause serious skin reactions, liver dysfunction, or muscle damage. If any adverse reactions occur, discontinue use and consult a healthcare professional immediately. Concomitant use with other drugs may increase blood concentration of this medication, raising the risk of muscle-related side effects. Therefore, any other medications being taken should be disclosed, especially since combination with fibrate drugs poses risks, and there may also be interactions with certain antiviral or antifungal medications. Pregnant or breastfeeding women should not take this medication, and women of childbearing potential should use appropriate contraception. In case of overdose, there is no specific antidote; symptom-based treatment is required, along with monitoring of liver function and muscle enzyme levels. Dizziness may occur during treatment; therefore, caution is advised when driving or operating machinery.

Serious side effects

Allergic reactions including urticaria and angioedema, rash and urticaria, pancreatitis, myopathy (including myositis), rhabdomyolysis, myalgia + CK elevation, thrombocytopenia, jaundice, hepatitis, Stevens-Johnson syndrome, eosinophilia with systemic symptoms associated drug reaction syndrome, immune-mediated necrotizing myopathy, hematuria, edema, acute renal failure, severe muscle weakness, ocular muscle weakness, severe skin adverse reactions, severe allergies

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• hematuria
• diarrhea

This medication should be stored in a tightly sealed container to protect it from exposure to air. The recommended storage temperature is between 1°C and 30°C at room temperature. Proper storage will help maintain the medication's efficacy.

Appearance

Pink round film-coated tablets

Package unit

30 tablets (15 tablets/PTP × 2)