Vimsc 150 mg (Lacosamide)

Adult dose

This medicine should be taken twice daily. The recommended initial dose is 50mg twice daily; after 1 week, increase the dose to 100mg twice daily. Depending on clinical response and tolerability, the maintenance dose may be increased each week by 50mg per dose, twice daily; the maximum recommended dose is 400mg per day (200mg per dose, twice daily). If treatment with this medicine is to be discontinued, gradual dose reduction is recommended. (e.g., gradually reduce the daily dose by 200mg each week) This medicine may be taken with or without food. 1. Patients with renal impairment No dose adjustment is required in patients with mild or moderate renal impairment (CLCR>30mL/min). A maximum dose of 300mg per day is recommended in patients with severe renal impairment (CLCR≤30mL/min) and end-stage renal disease. Since this medicine is removed from plasma by hemodialysis, an additional dose of up to 50% of the single dose is recommended immediately after hemodialysis for patients on hemodialysis. Treatment of patients with end-stage renal disease requires caution because clinical experience is limited and a metabolite (whose pharmacological activity is unknown) may accumulate. Dose adjustment should be made cautiously in all patients with renal impairment. 2. Patients with hepatic impairment The dose should be determined cautiously in patients with hepatic impairment. A maximum dose of 300mg per day is recommended in patients with mild or moderate hepatic impairment. Use is not recommended in patients with severe hepatic impairment. 3. Older adults Dose reduction is not required in older adults. Experience with lacosamide in older adults with epilepsy is limited; however, reduced renal clearance and increased AUC associated with age should be taken into consideration in older adults. (Refer to section 'Patients with renal impairment')

Child dose

Children and adolescents under 16 years of age: Use in these age groups is not recommended because data on the safety and efficacy of this medicine in children and adolescents under 16 years of age are unavailable.

This medication may increase the risk of suicidal thoughts or behaviors, so if any mood changes or abnormal behavior occur during treatment, immediate consultation with a physician is necessary. Do not take this medication if you are allergic to any of its components. Dizziness may occur, leading to a risk of falls, so caution is needed when starting treatment or adjusting the dose. Patients with heart issues or abnormal ECG must consult a physician before using this medication and report any cardiac symptoms immediately. If there are any mental health issues such as depression, suicidal thoughts, or mood changes during treatment, inform caregivers or healthcare professionals. Rarely, multi-organ hypersensitivity reactions such as rash, fever, hepatitis, or nephritis may occur, and in such cases, immediately discontinue use and inform healthcare providers. Common side effects include dizziness, headache, nausea, double vision, and these symptoms may improve over time. Avoid driving or operating dangerous machinery until dizziness or visual disturbances have completely resolved. This medication may interact with other drugs, so it is essential to inform healthcare providers of any other medications currently being taken. Elderly patients can generally take this medication without special dosing adjustments, but caution may be needed depending on their physical condition. Safety and efficacy in children and adolescents under 16 years have not been established, so its use is not recommended in this age group. During pregnancy, this medication may affect the fetus; hence, consult a physician before taking it if planning pregnancy or currently pregnant. Breastfeeding may cause this medication to be secreted in breast milk, so nursing should be discontinued or careful consideration should be given to its use. Overdose may result in symptoms such as dizziness, nausea, and vomiting, and as no specific antidote exists, immediate medical treatment should be sought. This medication has the potential to cause psychological dependence, so do not discontinue use or change the dose arbitrarily. Store this medication out of reach of children, and avoid transferring it to another container to maintain quality.

suicidal thoughts, suicidal behavior, depression, abnormal changes in mood and behavior, dizziness, ataxia, prolonged PR interval, second-degree or higher atrioventricular block, atrial fibrillation, atrial flutter, palpitations, slow or irregular pulse, fainting, double vision, headache, nausea, vomiting, constipation, gastric distension, dyspepsia, dry mouth, diarrhea, muscle cramps, itching, gait disturbances, asthenia, fatigue, irritability, feelings of intoxication, fever, falls, skin lacerations, bruising, neutropenia, anemia, syncope, bradycardia, abnormal liver function tests, agranulocytosis, drug hypersensitivity reactions, euphoric feeling, suicide attempts, aggression, anxiety, psychotic disorders, insomnia, hallucinations, cardiac asystole, cardiac arrest, death, toxic epidermal necrolysis, Stevens-Johnson syndrome, rash, angioedema, hives, seizures, ataxia, sedation, hair loss, blisters, early satiety, weight gain, decreased appetite, urinary incontinence, hiccups, coma, tonic-clonic seizures, status epilepticus, cardiac arrest, euphoric-type reactions

This medication should be stored in a tightly closed container to prevent air and moisture from entering, and it is best kept at room temperature between 1 and 30 degrees Celsius. In this way, the medication's effectiveness can be maintained for a long time.

Appearance

Peach-colored oval film-coated tablets

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 200 tablets/bottle