Clarithromycin 250 mg Tablet

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment period is 7～14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it must be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, or rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine three times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: Same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be administered to certain patients. For example, those with allergies to any of the ingredients or those who have had hypersensitivity reactions to certain antibiotics should avoid it. Patients with severe heart rhythm abnormalities or severely impaired liver or kidney function should also avoid this medication. Women who are pregnant or breastfeeding should not take this medication. Caution should be exercised when administering this medication to patients with impaired liver or kidney function, patients with heart disease, and the elderly. Those taking other antibiotics or with drug allergies should also be cautious. When taking this medication, various side effects may occur, such as allergic reactions, gastrointestinal issues, skin rashes, liver dysfunction, renal impairment, and central nervous system abnormalities, so any unusual symptoms should be reported to a doctor immediately. This medication has a high potential for interactions with other drugs, especially medications affecting heart rhythm, drugs metabolized in the liver, and blood coagulation-affecting medications; therefore, careful management according to a doctor's instructions is necessary when taken together. It is advisable to avoid this medication during pregnancy or breastfeeding, and if it must be used for some reason, consultation with a healthcare professional is required. In children, the safety and efficacy of this medication have not been adequately studied, so strict adherence to a doctor's prescription and guidance is essential. The elderly may have diminished bodily functions, necessitating dose adjustments and monitoring for side effects when taking this medication. Long-term or repeated use of this medication may lead to the development of resistant bacteria, so it should be administered only for the necessary duration, and monitoring for adverse reactions should be conducted after use. In case of overdose, gastrointestinal disturbances or central nervous system symptoms may appear, so strict adherence to the dosing schedule is essential, and any adverse effects should be promptly reported to a hospital. This medication should not be refrigerated; it should be stored at room temperature away from direct sunlight.

• Shock
• anaphylactic symptoms
• shortness of breath
• convulsions
• redness
• rash
• itching
• hives
• skin redness
• angioedema

This medication is sensitive to light and should be stored in a tightly sealed container to prevent light exposure. It is recommended to store it at room temperature between 15 to 30 degrees Celsius to maintain its efficacy for a long period.

Appearance

Yellow rectangular film-coated tablet

Package unit

100 tablets/bottle, 30 tablets/bottle