Samsung Sitagliptin Plus Tablet 50/1000 mg

Adult dosage

The usual dosage of this medication is taken twice daily with food, and the dose is gradually increased to reduce gastrointestinal side effects caused by Metformin. 1. For patients not currently receiving treatment with Metformin: Take this medication 50/500 mg twice daily, 1 tablet per dose, and if dose escalation is required, take 50/1000 mg twice daily, 1 tablet per dose. 2. For patients currently receiving Metformin: The recommended initial dosage of this medication for patients who cannot achieve sufficient blood sugar control with Metformin monotherapy is Sitagliptin 50 mg twice daily (total daily dose of 100 mg) together with the existing dose of Metformin.

This medication is used for the treatment of diabetes and contains two active ingredients: Sitagliptin and Metformin. Firstly, Sitagliptin can cause severe allergic reactions in some patients, so if symptoms such as rash or difficulty breathing occur, use should be discontinued immediately. Additionally, acute pancreatitis may occur, so if severe abdominal pain or vomiting occurs, consulting a doctor is necessary. Metformin can rarely cause a serious metabolic disorder called lactic acidosis, which requires prompt treatment. Patients with poor kidney function, heart failure, severe infections, or dehydration should not use this medication. Before and after undergoing tests with iodinated contrast agents, medication should be temporarily discontinued due to the risk of kidney damage and lactic acidosis. It is safest for pregnant or breastfeeding women to avoid taking this medication. Furthermore, irregular meals, intense exercise, or interactions with other medications can increase the risk of hypoglycemia or lactic acidosis, so caution is advised. While taking this medication, regular blood and kidney function tests should be conducted, and monitoring vitamin B12 levels is also recommended. Symptoms such as diarrhea, nausea, headache, and cold-like symptoms may occur, so if symptoms are severe, consulting a doctor is advised. In particular, when taking this medication with other diabetes medications such as insulin or sulfonylureas, hypoglycemic symptoms may occur more frequently, so blood sugar should be closely monitored. In case of surgery, medication should be stopped 48 hours prior to the procedure and resumed only after confirming that kidney function is normal post-recovery. Finally, this drug can also be used for the elderly, but dose adjustment and periodic testing are necessary due to declining kidney function. If symptoms such as sudden muscle pain, skin rash, or difficulty breathing occur while taking this medication, notify healthcare professionals immediately.

Serious side effects

• Urticaria
• angioedema
• anaphylaxis
• Stevens-Johnson syndrome
• rash
• severe allergic reactions
• acute pancreatitis
• severe lactic acidosis
• hypoglycemia
• difficulty breathing

Mild side effects

• Diarrhea
• upper respiratory infections
• headache
• nausea
• vomiting
• abdominal pain
• constipation
• nasopharyngitis
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent air from entering and kept at room temperature between 1°C and 30°C. This helps maintain the drug's effectiveness and ensures safe use.

Appearance

Dark red oval film-coated tablet

Package unit

28 tablets/bottle, 30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle