CDSCC Solution

Adult administration

1. Place 60-72 L of diluent water for dialysis into a suitable mixing container and dilute. 2. Slowly add 1 bag of yellow pack (Citric Acid Monohydrate) into the diluent and mix well. 3. Add 3 bags of gray pack (Sodium Chloride), 1 bag of blue pack (Magnesium Chloride), 1 bag of red pack (Calcium Chloride), 1 bag of brown pack (Potassium Chloride), and 1 bag of green pack (Glucose) into the mixture. 4. Add additional diluent water until the total solution reaches 100 L.

This drug should be used with caution in patients taking digitalis glycosides because low serum potassium may result in digitalis toxicity. During or after dialysis, hypoglycemic symptoms may occur due to low blood sugar, so if such symptoms appear, intravenous glucose should be administered or sugar intake should be supplemented immediately. Conversely, hyperglycemia may also occur, in which case dialysis should be done using a solution without glucose. The use of this medication may increase thirst, leading to excessive fluid intake, which can result in increased weight or elevated blood pressure. In such cases, ultrafiltration pressure should be adjusted to manage body fluids or weight. After or during dialysis, blood calcium levels may drop, leading to cramps or discomfort. In these cases, it may be necessary to switch to a dialysis solution with high calcium concentration or administer calcium supplements. Bone-related complications such as osteoporosis, osteomalacia, and fibrous osteitis may occur, requiring treatment such as the administration of active vitamin D3 preparations. Additionally, ectopic calcification may arise, necessitating the management of serum phosphate levels with phosphate binders to maintain them within the normal range. Dialysis disequilibrium syndrome may occur, presenting symptoms like headache, nausea, vomiting, cramps, and altered consciousness; in such cases, measures to reduce dialysis efficiency may be necessary. This drug can affect the cardiovascular system, with low blood pressure or shock symptoms possibly emerging, in which case dialysis may need to be stopped or the efficiency lowered, and appropriate treatment such as intravenous fluids or blood pressure-raising agents administered. Although rare, blood pressure may rise, necessitating the administration of antihypertensives or changes in dialysis solution. This drug is used for hemodialysis in patients with chronic renal failure, particularly when high acetate dialysis solutions are ineffective for metabolic acidosis or when side effects such as low blood pressure or disequilibrium syndrome occur. It is also used when glucose control is difficult, employing solutions containing glucose. It is utilized to treat solutions with low potassium, calcium, and magnesium concentrations when hyperkalemia or hypermagnesemia is not improved. Care should be taken as high calcium levels may cause hypercalcemia. Regular blood tests to check electrolytes, acid-base balance, blood sugar levels, etc., are essential. During or after dialysis, monitoring changes in serum citric acid, calcium levels, oxygen, and carbon dioxide concentrations is crucial. Pregnant women or those who may become pregnant should only use this drug when the benefits of treatment outweigh the potential risks, as its safety has not been established. Safety in pediatric patients has also not been established, so it should be used with caution. Elderly patients may experience bone complications, thus appropriate management with regular clinical examinations and administration of active vitamin D3 preparations is recommended. Patients with aluminum bone disease should be monitored for bone density, and high calcium dialysis solutions should be employed as necessary. Dialysis water for preparation should strictly meet specified standards, and attention should be given to the risk of bleeding due to anticoagulant use or membrane damage. During preparation, use electrolyte solutions for artificial kidney dialysis and sodium bicarbonate solutions carefully; they should not be used alone, but properly diluted as prescribed. If concentrations are too high or low, symptoms such as headache, palpitations, changes in blood pressure, and altered consciousness may occur. Check the electrolyte concentrations, osmotic pressure, pH of the dialysis solution, and use it immediately afterward, never storing for longer than 2 hours. Do not use if insoluble substances are detected. The dialysis solution should be warmed to body temperature prior to use and is not meant for injections or peritoneal dialysis. It is crucial to closely monitor the patient's condition while using this drug, taking appropriate action as necessary.

Serious side effects

Altered consciousness, shock symptoms.

Mild side effects

Hypoglycemia, hyperglycemia, weight gain, tendency to increase blood pressure, cramps and discomfort due to hypocalcemia, osteoporosis, osteomalacia, fibrous osteitis, ectopic calcification, headache, nausea, vomiting, cramps, altered consciousness, discomfort, fatigue, low blood pressure, shock symptoms, elevated blood pressure.

This drug should be stored in a tightly sealed container to protect it from air or moisture, ideally at room temperature between 1°C and 30°C. Maintaining the proper temperature and container conditions will help ensure the medication's effectiveness safely.

Appearance

1 box contains 6 types (8 pieces) of bags, with each bag characterized as follows: - Colorless or white powder packaged in polyethylene film bags of gray (Sodium Chloride) - 3 bags - Blue (Chloride)

Package unit

28.012 kg