Solitaire Tablet 10 mg (Solefenacin Succinate)

Adult dose

The usual recommended dose for adults (including elderly patients) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken with or without food and should be swallowed whole with water. Patients with renal impairment No dosage adjustment is necessary in patients with mild or moderate renal impairment (creatinine clearance>30ml/min). In patients with severe renal impairment (creatinine clearance≤30ml/min), administer with caution and do not exceed 5mg once daily. Patients with hepatic impairment No dosage adjustment is necessary in patients with mild hepatic impairment. In patients with moderate hepatic impairment (Child-Pugh class B), administer with caution and do not exceed 5mg once daily. Patients taking a strong cytochrome P450 3A4 (CYP3A4) inhibitor For patients taking ketoconazole or another strong CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication should not be used in patients with symptoms of urinary retention. Patients with severe gastrointestinal disorders or myasthenia gravis should also avoid this medication. Patients with glaucoma, who have high eye pressure, or those allergic to any of the ingredients should not use it. Additionally, patients who are undergoing dialysis or have severely impaired liver or kidney function should avoid this medication. It is also unsuitable for patients with genetic issues such as lactose intolerance. This medication should be used cautiously in patients at risk of urinary obstruction, those with gastrointestinal obstruction diseases, and those at risk of slowed gastrointestinal motility. Patients with moderately impaired kidney or liver function should limit the maximum daily dose, and caution is also necessary when taking it with certain potent medications. Patients taking medications that can induce or worsen gastroesophageal reflux or esophagitis should exercise caution. Patients with autonomic nervous system disorders should also be cautious when using this medication. This medication may cause dry mouth, constipation, and blurred vision. In rare cases, serious gastrointestinal issues may arise, so any unusual symptoms should be reported immediately. The degree of adverse reactions does not significantly change even with prolonged use, and dry mouth is a common reason for discontinuation. This medication can cause drowsiness or fatigue and blurred vision, so caution is advised when driving or operating machinery. In case of severe allergic reactions like angioedema or anaphylaxis, discontinue the medication immediately and seek treatment. This medication can enhance the effects or increase side effects when used with other anticholinergic drugs, so caution is warranted. It may also reduce the effectiveness of gastrointestinal motility-promoting medications. The medication is metabolized in the liver, so using it in patients with poor liver function or with certain strong liver enzyme inhibitors may result in elevated drug levels. In such cases, the dosage should be reduced, and patients with severe liver or kidney disease should preferably avoid concurrent use. The safety of this medication during pregnancy has not been established, so caution is necessary when taking it. Breastfeeding mothers should avoid this medication as it may pass into breast milk and affect the baby. This medication has not been confirmed for safety and efficacy in pediatric patients, so it should not be administered to them. Overdose may result in symptoms such as headache, dizziness, drowsiness, and blurred vision, and severe cases may require professional treatment. In cases of overdose, gastric lavage or inducing vomiting is not performed, and treatment may involve antidotes or symptomatic care as needed. This medication is known not to increase the risks of genotoxicity or cancer development even with long-term use. It has been shown in animal studies not to affect reproductive ability or fetal development.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colonic obstruction
• intestinal obstruction
• vascular neurogenic edema
• nausea

Store this medication in a tightly sealed container, avoiding exposure to air or moisture. It is best to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and ensure safe use.

Appearance

Light pink round film-coated tablet

Package unit

100 tablets/PTP (10 tablets/PTP x 10)