Clarithromycin 500 mg Tablet

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this medicine to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) twice daily. In this case, this medicine should be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine three times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14) and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: same as adults For children under 12 years, use clarithromycin dry syrup.

This medicine should not be administered to patients with certain medications or conditions. For example, patients with allergies to any of the components of this medicine or those with certain heart diseases, severe liver dysfunction, or significantly reduced kidney function may be at risk if they use this medication. Additionally, it is advisable for pregnant or nursing women to avoid taking this medicine, as it can affect the baby. When using this medication, careful monitoring of liver and kidney function is necessary, and patients with heart disease should use it cautiously, considering the potential for heart problems such as arrhythmias. This medicine can interact with various other medications, so if you are taking other medicines, it is essential to inform your doctor or pharmacist. Special caution is needed when used in conjunction with specific heart medications, anticoagulants, anticonvulsants, immunosuppressants, etc. While taking this medicine, symptoms such as allergic reactions, gastrointestinal disturbances, liver dysfunction, reduced kidney function, and central nervous system abnormalities may occur; if these symptoms arise, you should consult a healthcare professional immediately. In cases of overdose, gastrointestinal symptoms or changes in mental state may appear, requiring immediate emergency treatment. Finally, the safety of this medicine for children, especially those under 12 years of age, has not been thoroughly studied, so special caution is needed when administering it to children.

Shock, anaphylactic symptoms, respiratory distress, convulsions, flushing, rash, itching, urticaria, mild skin flushing, angioedema, joint swelling, drug rash, abdominal distention, nausea, vomiting, dyspepsia, abdominal pain, malaise, bloating, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste alteration, decreased appetite, constipation, stool discoloration, membrane colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, acute exacerbation of maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucination, psychosis, dissociation, tremor, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increase in liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, increased LDH, elevated ALP, increased total bilirubin, decreased appetite, dark urine, itching, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, elevated CPK, elevated serum myoglobin, elevated urinary myoglobin, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste disorders, hearing loss, paresthesia, arthralgia, myalgia, olfactory disorders, tinnitus, auditory impairment, hypoglycemia, tinnitus, hearing impairment, vomiting, purpuric rash, acute generalized pustular psoriasis, venous inflammation at the injection site, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increased serum alkaline phosphatase, increased serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color

This medicine is sensitive to light and should be stored in a special container protected from light. Additionally, it is important to store it at room temperature between 15 and 30 degrees Celsius to maintain its effectiveness.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle