Medication info
Minurin 0.1 mg (Desmopressin Acetate)

Minurin 0.1 mg (Desmopressin Acetate)

Prescription medicationTabletOral
Ingredient · strength
Desmopressin Acetate›0.1mg / 1 tablet
Manufacturer / importer
Hana Pharmaceutical Co., Ltd.
Appearance
White, convex, oval-shaped tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 201603987 · Approved 2016.06.27 · Insurance code 657805850

Summary

Main use
Treatment of primary nocturnal enuresis (age 5 years and older) and nocturia associated with nocturnal polyuria (adults)
Who takes it
Adults · Children
Adult dose
Treatment of symptoms of nocturia associated with nocturnal polyuria (adults only) : Administer desmopressin acetate 0.1mg orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, increase the dose at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose determination. Initiation of treatment with this medication is not recommended in patients aged 65 years or older. If treatment is required in an older adult, closely monitor serum sodium levels and other parameters. (See Precautions for Use, 5. General Precautions)
Child dose
Primary nocturnal enuresis (age 5 years and older) : Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Decide whether to continue treatment after 3 months of administration, following a treatment-free period of at least 1 week.

Ingredients

Manufacturer
Hana Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of primary nocturnal enuresis (age 5 years and older) and nocturia associated with nocturnal polyuria (adults)

  • Primary nocturnal enuresis
  • nocturia
  • nocturia symptoms
View approved original text

This medication is primarily used for the treatment of primary nocturnal enuresis in children over 5 years old and nocturia symptoms associated with nocturia in adults. In simpler terms, it helps improve the symptoms of frequent urination at night. When such symptoms are present, this medication can aid in achieving comfortable sleep and enhancing quality of life. It is used to reduce the discomfort caused by nocturia and to restore normal urination habits.

How to take

Adult dose

Treatment of symptoms of nocturia associated with nocturnal polyuria (adults only) : Administer desmopressin acetate 0.1mg orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, increase the dose at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose determination. Initiation of treatment with this medication is not recommended in patients aged 65 years or older. If treatment is required in an older adult, closely monitor serum sodium levels and other parameters. (See Precautions for Use, 5. General Precautions)

Child dose

Primary nocturnal enuresis (age 5 years and older) : Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Decide whether to continue treatment after 3 months of administration, following a treatment-free period of at least 1 week.

Precautions

This medication can affect the balance of fluids and electrolytes in the body, so especially in elderly patients or those with high fluid intake, it is important to drink water only to the extent of feeling thirsty to prevent hyponatremia and fluid overload. Patients who have had allergic reactions to this medication or those with certain kidney diseases, heart failure, or those on diuretics should not use this medication. Patients with decreased kidney function, hypertension, cardiovascular diseases, pregnant women, children, and the elderly should use this medication with extra caution, and thorough monitoring and testing by a doctor are needed if necessary. This medication can cause serious symptoms of fluid overload, such as coma, seizures, and weight gain, so if these symptoms occur, immediate consultation with healthcare professionals is required. Fluid intake should be limited from 1 hour before administration to 8 hours after administration, and excessive fluid intake can lead to dangerous side effects. Interactions can occur if taken with other medications, so particularly when combined with antidepressants, diuretics, corticosteroids, and anti-inflammatory analgesics, tests and observation of condition according to the doctor's instructions are necessary. Women who are pregnant or may become pregnant should discuss the necessity of using this medication with their doctor, weighing the risks and benefits, and breastfeeding women are advised to discontinue breastfeeding. In case of overdose, symptoms such as headache, nausea, seizures, and loss of consciousness may occur, so immediate hospital visit for appropriate treatment is required if symptoms arise.

Side effects

  • coma
  • convulsions
  • weight gain
  • severe water intoxication
  • hyponatremia
  • allergic reactions
  • emotional disturbances
  • headache
  • abdominal pain
  • nausea
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  • allergic skin reactions
  • dizziness
  • peripheral edema
  • polyuria
  • thirst
  • anaphylaxis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air or moisture. It should be kept at room temperature, between 1 to 30 degrees Celsius. This will safely maintain the effectiveness of the medication.

Appearance and packaging

Appearance

White, convex, oval-shaped tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.