Rimeformin Tablet 2/500mg (Glimepiride, Metformin Hydrochloride)

Adult dose

This medication is administered 1 to 2 times a day before or with meals. Dosage may be adjusted based on each patient's current treatment regimen, effectiveness, and tolerability. Based on blood sugar monitoring results, the dose may gradually increase up to 8mg/2000mg of Glimepiride/Metformin Hydrochloride. If used as an alternative therapy for combination therapy, the dosage and regimen of the currently used Glimepiride and Metformin Hydrochloride should be considered.

This medication can cause severe lactic acidosis or hypoglycemia, so care should be taken especially if kidney function declines severely. If symptoms of dehydration occur, it is advisable to temporarily discontinue the medication and consult a physician. Patients with reduced kidney function or elderly individuals should undergo kidney function tests before using this medication and continue to have regular assessments of kidney function during treatment. Patients at risk of cardiovascular disease should consult with their physician to develop a treatment plan when taking this medication. Insulin-dependent diabetes patients, acute metabolic acidosis patients, patients with severe liver dysfunction, and women who are pregnant or breastfeeding should not use this medication. Patients with drug hypersensitivity or specific genetic metabolic disorders should also avoid taking this medication. This medication may cause hypoglycemia, so special caution is required for individuals with poor nutritional status, those skipping meals, excessive alcohol consumers, or patients with severely impaired liver function. Gastrointestinal disorders, taste disturbances, skin rash, and other side effects may appear, so if symptoms are severe, consult a physician. It is advisable to have regular blood tests since hematological abnormalities or vitamin B12 deficiency can occur. As there are many drug interactions, if you are taking other medications, be sure to inform your physician or pharmacist. Extra caution should be taken when taking this medication with drugs or alcohol that may affect kidney function. Women planning to become pregnant or who are currently pregnant should be treated with insulin instead of this medication for safety. Children and elderly individuals need special care when taking this medication, requiring dosage adjustments and regular testing. In case of overdose, hypoglycemia or lactic acidosis may occur, so contact a medical facility immediately for appropriate treatment. During the use of this medication, it is important to maintain regular meals and exercise, and to periodically monitor blood sugar and kidney function. Care should be taken when driving or operating machinery due to the risk of hypoglycemia.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe edema accompanied by increased blood pressure, yellowing of the skin or eyes (jaundice), liver function impairment, severe hypoglycemic symptoms, lactic acidosis, sudden and very severe headaches, visual disturbances, paralysis, seizures, confusion, coma, deep vein thrombosis, cardiac arrest, thrombocytopenic purpura, platelet count below 10,000/μL.

Mild side effects

Diarrhea, nausea, vomiting, abdominal distension, loss of appetite, indigestion, constipation, abdominal pain, taste disturbance, metallic taste, temporary visual disturbances due to changes in blood sugar levels, erythema, itching, rash, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, agranulocytosis, pancytopenia, vitamin B12 deficiency, elevation of liver enzymes, hepatitis, allergic vasculitis, photosensitivity of the skin, decreased serum sodium concentration.

This medication should be stored in a tightly closed container to prevent air and moisture from entering, and it is recommended to keep it at room temperature between 1°C and 30°C. Proper storage helps maintain the drug's effectiveness over time.

Appearance

White oblong film-coated tablets

Package unit

30 tablets/PTP [(10 tablets/PTP x 3)], 100 tablets/bottle, 30 tablets/bottle