Lefloxacin Tablet (Ofloxacin)

Adult dosage

○ The usual adult dose of ofloxacin is 300～600 mg per day, divided into 2～3 doses. ○ For Hansen's disease, the dose of this medicine is 400～600 mg per day, divided into 2～3 doses. In principle, it should be used in combination with other antileprosy drugs. The dose may be adjusted as appropriate according to age and symptoms.

This medication may cause tendon problems such as tendinitis and tendon rupture; therefore, if these symptoms occur, it should be discontinued immediately. It may also affect peripheral neuropathy or the central nervous system, so caution is needed if sensory abnormalities or neurological symptoms arise. Patients with myasthenia gravis should not use this medication as it may worsen their symptoms. Elderly patients, patients with impaired kidney function, and those taking corticosteroids should avoid combination therapy due to an increased risk of tendon damage. This medication should not be used by pregnant or breastfeeding women, growing children, or adolescents, and patients with certain genetic diseases should also avoid taking it. It may increase the risk of seizures, so caution is required for patients with epilepsy or a history of seizures. During treatment, regular checks of liver and kidney function are necessary, and adequate hydration is required. Avoid excessive exposure to sunlight or artificial UV light, and if skin rashes or phototoxic reactions occur, discontinue use immediately. This medication may cause neurological side effects such as dizziness or drowsiness, so caution is needed when driving or operating machinery. It may affect blood sugar control, so diabetic patients should check their blood sugar frequently and seek treatment immediately if symptoms of hypoglycemia occur. Additionally, there are many interactions with other medications, especially with anticoagulants, certain anti-inflammatory drugs, and antacids, so consult with a doctor or pharmacist when taking these together. Store this medication out of the reach of children, and it is advisable not to transfer it to another container.

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactoid reactions, rash, itching, erythema, edema, fever, warmth, blisters, erythema, photosensitivity reactions, hematuria, acute renal failure, nephrolithiasis, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, hepatic failure, elevated AST/ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, cholestatic jaundice, fulminant hepatitis, membranous colitis, colitis with hematochezia, abdominal pain, frequent diarrhea, nausea, vomiting, gastrointestinal discomfort, diarrhea, cirrhosis, anorexia, upper abdominal pain, indigestion, chest pain, thirst, taste disturbance, stomatitis, lingual inflammation, abdominal distension, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombotic thrombocytopenic purpura, petechial and purpuric hemorrhage, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, elevated ESR, insomnia, dizziness, headache, seizures, tremors, numbness, peripheral neuropathy, visual disturbances, auditory disturbances, hallucinations, drowsiness, neuroexcitability, sleep disturbances, confusion, anxiety, depression, restlessness, hyperesthesia, delirium, suicidal thoughts, suicide, perceptual disturbances, reversible olfactory and equilibrium sensory disturbances, ataxia, aphasia, heaviness of the head, mucocutaneous syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscle weakness, myositis, asthenia, elevated CPK, elevated serum and urinary myoglobin, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, epistaxis, stridor, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, polyuria, urinary retention, anuria, polyuria, hematuria, urinary storage, pyuria, diabetes, proteinuria, alkaluria, vaginitis, vaginal candidiasis, increased vaginal discharge, pruritus of the female external genitalia, menstrual irregularities, uterine cramps, female genital rash, pain, irritation, burning sensation, symptoms of hypoglycemia, limb pain, malaise, fever, drowsiness, nausea, dizziness, facial flushing, facial swelling, numbness, inaccurate pronunciation, moderate loss of sense of direction

This medication should be stored in a tightly sealed container to protect it from air and moisture, at a temperature between 1 to 30 degrees Celsius. Storing it in this manner will help maintain its effectiveness and prevent deterioration.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle