Medication info
Ilseong Clarithromycin Tablet 250mg

Ilseong Clarithromycin Tablet 250mg

Prescription medicationTablet
Ingredient · strength
Clarithromycin›250mg / 1 tablet
Manufacturer / importer
Ilseong IS Co., Ltd.
Appearance
Yellow oblong film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201603545 · Approved 2016.06.17 · Insurance code 655403620

Summary

Main use
Treatment of infections (respiratory, skin, and mycobacterial infections) and Helicobacter pylori infection associated with duodenal ulcers
Who uses it
Adults · Children
Adult dosage
Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7~14 days. In patients with renal failure whose creatinine clearance is 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: For 14 days, administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1~14), and omeprazole 40mg once daily for 28 days (days 1~28).
Children's dosage
Children aged 12 years and older: Same as adults Children under 12 years of age: Use clarithromycin dry syrup.

Ingredients

Manufacturer
Ilseong IS Co., Ltd.

Efficacy & effects

Treatment of infections (respiratory, skin, and mycobacterial infections) and Helicobacter pylori infection associated with duodenal ulcers

  • Bronchitis
  • pneumonia
  • pharyngitis
  • sinusitis
  • skin and soft tissue infections
  • mycobacterial infections
  • duodenal ulcer
View approved original text

This medication is effective against various bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, and Influenza bacillus. It is used to treat lower respiratory tract infections like bronchitis and pneumonia, as well as upper respiratory tract infections such as pharyngitis and sinusitis. It is also effective for skin and soft tissue infections and helps with mycobacterial infections including Mycobacterium avium and intracellular infections. It is also used to eradicate Helicobacter pylori in patients with duodenal ulcers to improve symptoms. Thus, it is used effectively to treat various complex bacterial infections.

Dosage and Administration

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7~14 days. In patients with renal failure whose creatinine clearance is 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: For 14 days, administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1~14), and omeprazole 40mg once daily for 28 days (days 1~28).

Children's dosage

Children aged 12 years and older: Same as adults Children under 12 years of age: Use clarithromycin dry syrup.

Precautions

This medication should not be given to certain patients. Patients with allergies to any of the ingredients in this medication or a history of allergy to antibiotics in the same class should not use this medicine. Additionally, patients with certain heart conditions or severely impaired liver or kidney function, and pregnant or breastfeeding women should not use this medication. Patients currently taking other medications that may affect heart rhythm should also avoid this drug. This medication should be used cautiously in patients with impaired liver or kidney function, those with heart disease, the elderly, and those taking other antibiotics. Care should also be taken with a history of drug allergies. During treatment, there may be rare instances of severe allergic reactions, skin rashes, gastrointestinal disturbances, liver function abnormalities, kidney issues, central nervous system symptoms, etc., and if these symptoms occur, medical consultation should be sought immediately. To prevent antibiotic resistance, it is essential to verify the susceptibility of the infecting bacteria and only take the medication for the necessary minimum duration. Moreover, this medication may interact with other drugs, so it is crucial to inform healthcare professionals of any concurrent medications. Pregnant or breastfeeding women should not use this medication, and breastfeeding should be discontinued if necessary. Children and the elderly require special precautions when using this medication; in particular, elderly patients with reduced kidney function may need dosage adjustment. Regular monitoring such as liver function tests, kidney function tests, and blood tests may be necessary during treatment. Overdosage may lead to gastrointestinal symptoms or central nervous system abnormalities; thus, prompt medical attention should be sought for appropriate treatment. This medication should be stored away from direct sunlight and kept at room temperature; refrigeration is not recommended.

Side effects

  • Shock
  • anaphylaxis symptoms
  • shortness of breath
  • seizures
  • flushing
  • rash
  • itching
  • hives
  • skin flushing
  • angioedema
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  • joint swelling
  • drug rash
  • abdominal distension
  • nausea
  • vomiting
  • dyspepsia
  • abdominal pain
  • discomfort
  • flatulence
  • diarrhea
  • oral mucosal erosion
  • upper abdominal pain
  • thirst
  • transient teeth discoloration
  • pancreatitis
  • increased amylase
  • dysgeusia
  • decreased appetite
  • constipation
  • stool discoloration
  • pseudomembranous colitis
  • hemorrhagic colitis
  • fever
  • cough
  • abnormal chest X-ray
  • eosinophilia
  • eosinophilic lung infiltration
  • interstitial pneumonia
  • chronic bronchitis
  • acute maxillary sinusitis
  • leukopenia
  • thrombocytopenia
  • pancytopenia
  • hemolytic anemia
  • agranulocytosis
  • dizziness
  • depression
  • taste loss
  • smell loss
  • anxiety
  • insomnia
  • nightmares
  • tinnitus
  • confusion
  • disorientation
  • hallucinations
  • psychosis
  • depersonalization
  • tremors
  • numbness
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • allergic purpura
  • drug rash
  • jaundice
  • hepatocellular hepatitis
  • cholestatic hepatitis
  • increased liver enzymes
  • liver dysfunction
  • liver failure
  • fulminant hepatitis
  • elevated AST
  • elevated ALT
  • elevated γ-GTP
  • elevated LDH
  • elevated ALP
  • increased total bilirubin
  • increased serum creatinine
  • elevated BUN
  • interstitial nephritis
  • kidney failure
  • rhabdomyolysis
  • glossitis
  • stomatitis
  • oral candidiasis
  • QT prolongation
  • ventricular tachycardia
  • Torsades de pointes
  • malaise
  • headache
  • taste disorders
  • hearing loss
  • paresthesia
  • arthralgia
  • myalgia
  • olfactory disorders
  • hypoglycemia
  • tinnitus
  • hearing impairment
  • purpuric rash
  • acute generalized pustular psoriasis
  • muscle cramps
  • musculoskeletal stiffness
  • myopathy
  • elevated blood urea
  • venous phlebitis at injection site
  • injection site pain
  • injection site inflammation
  • fever
  • asthenia
  • chest pain
  • chills
  • fatigue
  • abnormal albumin/globulin ratio
  • increased serum alkaline phosphatase
  • increased serum lactate dehydrogenase
  • increased International Normalized Ratio
  • prolonged prothrombin time
  • abnormal urine color

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature to preserve the medication's efficacy and safety for an extended period.

Appearance and packaging

Appearance

Yellow oblong film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.