Rosuvastatin Tablets 5 mg (Rosuvastatin Calcium)

Adult dosage

For patients with primary hypercholesterolemia, mixed dyslipidemia, dysbetalipoproteinemia, and homozygous familial hypercholesterolemia, the initial dose of 5 mg should be administered once daily at any time regardless of meals. If necessary, maintenance doses can be adjusted up to 10 mg once daily, with adjustments made based on patient response at intervals of 4 weeks or more, allowing a maximum daily dose of up to 20 mg.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the dosing is from 5 mg to 20 mg once daily, adjusted individually according to therapy goals at intervals of 4 weeks or longer.

This medication should not be used in certain patients. For example, it should not be administered to patients with allergies to its components, severely impaired liver function, and those with muscle problems. It also should not be used in patients with severely impaired kidneys, pregnant or nursing women, or fertile women who are not using appropriate contraception. This medication may affect liver function or muscle, so caution is warranted in patients with a history of liver disease or heavy alcohol consumption. If symptoms such as muscle pain or weakness occur, patients should report them to a physician immediately and undergo examination. This medication may raise blood glucose levels in some patients, so it is advisable for those at high risk of diabetes to monitor their blood sugar regularly. This medication may interact with other medications; patients should inform their doctor or pharmacist of any medications being taken. Interactions particularly with some antivirals, immunosuppressants, and antifungals may increase the risk of muscle problems. Pregnant or nursing women should not take this medication, and women of childbearing potential should employ adequate contraception. In case of overdose, there is no specific antidote; treatment should be based on symptoms, and liver function and muscle enzyme levels should be monitored regularly. Dizziness may occur while taking this medication, so caution is required when driving or operating machinery. If symptoms such as severe rash, swelling, or difficulty breathing occur during treatment, the medication should be stopped immediately and medical consultation sought.

Serious side effects

Hypersensitivity reactions including urticaria and angioedema, severe muscle weakness, oculobulbar weakness, rhabdomyolysis, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, fatal and non-fatal liver failure, polyneuropathy, severe edema, acute renal failure, oliguria, thrombocytopenia, severe allergic reactions, severe skin adverse reactions, dyspnea, respiratory issues, hepatic abnormalities

Mild side effects

Headache, dizziness, constipation, nausea, abdominal pain, itching, rash, urticaria, muscle pain, myopathy, rhabdomyolysis, weakness, hypersensitivity reactions including angioedema, hematuria, thrombocytopenia, fatigue, numbness, paresthesia, chest discomfort, diarrhea, appetite loss, abdominal bloating, abnormal liver function tests, syncope, generalized pain, muscle cramps, gout, erectile dysfunction, joint pain, memory loss, peripheral neuropathy, cough, depression, sleep disorders, sexual dysfunction

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. This helps retain the medication's effectiveness and safety for a longer period.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle