Medication info
Maphron Tablet (Limaprost Aldex)

Maphron Tablet (Limaprost Aldex)

Prescription medicationTablet
Ingredient · strength
Limaprost Alfadex›166.67μg / 1 tablet
Manufacturer / importer
Teragen Etex Co., Ltd.
Appearance
White round tablet
Packaging
21 tablets/blister [X 4]
Approval status
Active

MFDS item code 201603436 · Approved 2016.06.14 · Insurance code 698503510

Summary

Main use
Improvement of symptoms and walking ability in lumbar spinal stenosis; improvement of ischemic symptoms in Buerger's disease
Who uses it
Adults
Adult dosage
1. For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets per dose, 3 times daily by mouth. 2. For improvement of subjective symptoms (lower limb pain and numbness) and walking ability due to acquired lumbar spinal canal stenosis (patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet per dose, 3 times daily by mouth. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Teragen Etex Co., Ltd.

Efficacy & effects

Improvement of symptoms and walking ability in lumbar spinal stenosis; improvement of ischemic symptoms in Buerger's disease

  • Ulcers
  • pain
  • cold sensation
  • leg pain
  • numbness in legs
View approved original text

Helps improve ischemic symptoms such as ulcers, pain, and cold sensation caused by occlusive thromboangiitis. It is also used to alleviate subjective symptoms such as leg pain and numbness that occur due to post-acquired lumbar spinal canal stenosis, and to enhance walking ability.

Dosage and Administration

Adult dosage

1. For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets per dose, 3 times daily by mouth. 2. For improvement of subjective symptoms (lower limb pain and numbness) and walking ability due to acquired lumbar spinal canal stenosis (patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet per dose, 3 times daily by mouth. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medication should not be used in women who are pregnant or may become pregnant. This medication contains lactose, so it should not be administered to patients with a genetic disorder that causes lactose intolerance. Patients with a tendency to bleed or those taking medications that affect blood clotting should use this medication with caution. Allergic reactions such as skin rash or itching may occur with this medication, so it should be discontinued immediately if such symptoms appear. There may be rare occurrences of bleeding, so bleeding symptoms should be carefully monitored. Gastrointestinal discomfort may occur, including diarrhea, nausea, abdominal pain, appetite loss, and heartburn. Due to the potential effect on liver function, it is necessary to regularly check for elevated liver enzyme levels. Cardiovascular symptoms such as rapid heartbeat or low blood pressure may occur. A variety of side effects have been reported, including headaches, facial flushing, dizziness, warmth sensation, fatigue, swelling, tremor, increased body hair on the legs, and anemia. Patients with lumbar spinal canal stenosis should carefully observe symptoms and decide on the continued use of this medication. Safety has not been established during pregnancy, and uterine contractions have been observed in animal studies, so it is not used in pregnant women. Safety has not been confirmed in children, and there is no experience in use. Elderly patients may have weakened physical function, so caution should be exercised by possibly reducing the dosage. High doses in healthy adults may temporarily lower blood pressure, so caution is required.

Side effects

  • Rash
  • itching
  • bleeding
  • diarrhea
  • nausea
  • abdominal discomfort
  • abdominal pain
  • loss of appetite
  • heartburn
  • vomiting
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  • abdominal bloating
  • elevated AST (GOT)
  • elevated ALT (GPT)
  • palpitations
  • peripheral cyanosis
  • low blood pressure
  • headache
  • facial flushing
  • dizziness
  • feeling of warmth
  • generalized malaise
  • edema
  • mastitis
  • body tremors
  • hirsutism
  • anemia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. This helps to preserve the effectiveness and safety of the medication.

Appearance and packaging

Appearance

White round tablet

Package unit

21 tablets/blister [X 4]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.