Amapi LM Tablets 2/500 mg

Adult dose

This medication is taken 1 to 2 times a day before meals or with meals. The dosage may be adjusted according to the current treatment regimen, efficacy, and tolerability of each patient, with appropriate blood glucose monitoring required. The initial dose is Glimepiride / Metformin Hydrochloride 2 mg/500 mg, and can be gradually increased up to a maximum of 8 mg/2000 mg. When using the monotherapy Glimepiride, the usual dose is more than 4 mg per day.

This medication may cause severe lactic acidosis or hypoglycemia, and should be discontinued if kidney function declines sharply. It is advisable to temporarily stop taking this medication and consult a physician if dehydration occurs due to diarrhea, vomiting, or fever. Care should be taken when using this medication in patients with impaired kidney function or those taking medications that may affect the kidneys. Patients with cardiovascular disease should discuss cardiovascular risks with their doctor before and after taking this medication. This medication should not be used in patients with insulin-dependent diabetes, acute metabolic acidosis, severe liver dysfunction, pregnant or breastfeeding women, or those with severe kidney impairment. As this medication can cause hypoglycemia, especially patients with poor nutritional status or irregular eating habits, the elderly, and those with liver dysfunction should be carefully observed for hypoglycemic symptoms. Gastrointestinal disturbances (diarrhea, nausea, vomiting, etc.) may occur at the beginning of treatment, but are usually temporary and can be alleviated by taking it with meals. If allergic reactions, skin rashes, or breathing difficulties occur, inform a doctor immediately. This medication may reduce vitamin B12 levels, so it is recommended to have regular vitamin B12 tests during long-term use. There may be interactions with other medications, so it is essential to consult healthcare professionals when starting or stopping new medications. Do not use this medication during pregnancy or breastfeeding; instead, insulin therapy should be considered if necessary. In children or the elderly, regular kidney function tests are necessary, and dose adjustments may be required. In case of overdose, hypoglycemia or lactic acidosis may occur, so inform healthcare professionals immediately and receive appropriate treatment. When driving or operating machinery, caution is advised due to the risk of accidents from hypoglycemia or dizziness. This medication should be stored out of reach of children, and care should be taken not to transfer it to other containers.

Serious side effects

• Hives
• severe swelling
• chest tightness
• difficulty breathing
• hypotension
• severe allergic reactions
• severe swelling
• thrombocytopenic purpura
• platelet count below 10
• 000/μL

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal bloating
• loss of appetite
• dyspepsia
• constipation
• abdominal pain
• abdominal fullness
• metallic taste

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is best to store it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness over time.

Appearance

White oblong film-coated tablet

Package unit

30 tablets/bottle - 30 tablets/bottle[30 tablets/bottle], 100 tablets/bottle - 100 tablets/bottle[100 tablets/bottle]