RanoPensia Tablet

Adult dose

Children over 12 years old and adults: Dosage should be adjusted according to the severity of pain and therapeutic response. A starting dose of 4 tablets is recommended, and subsequent administration intervals should be at least 6 hours apart, not exceeding 16 tablets per day. Administer the lowest effective dose for the shortest duration possible. Avoid prolonged use of this drug beyond what is necessary, and if long-term administration is required due to the characteristics and severity of the disease, regular monitoring should be conducted to assess the need for continuous use of this medication. Elderly Administer the usual adult dose. However, in elderly patients over 75 years of age, oral administration of tramadol may increase the half-life clearance by 17%, so administration should be at least every 6 hours apart. Renal impairment patients For patients with moderate renal impairment (creatinine clearance of 10-30ml/min), extend the administration interval to 12 hours. For severe renal impairment patients (creatinine clearance of less than 10ml/min), administration is not recommended. Tramadol is removed very slowly during hemodialysis and filtration, therefore, there is no need for re-administration of this medication after dialysis for pain relief. Hepatic impairment patients It should be carefully considered to extend the administration interval in moderate hepatic impairment patients. This medication should not be administered to patients with severe hepatic impairment.

Child dose

Children over 12 years old and adults: Dosage should be adjusted according to the severity of pain and therapeutic response. A starting dose of 4 tablets is recommended, and subsequent administration intervals should be at least 6 hours apart, not exceeding 16 tablets per day.

This drug may cause liver damage in individuals who regularly consume more than three drinks a day. Consultation with a doctor or pharmacist is essential. This medication can rarely cause serious skin reactions; if skin rash or hypersensitivity symptoms occur, discontinue use immediately and seek medical care. The ingredients in this drug can increase the risk of seizures, so patients with a history of seizures or those taking seizure-inducing medications should be cautious. Rarely, severe allergic reactions have been reported; if symptoms such as difficulty breathing or skin rash occur, visit a medical facility immediately. This medication may pose a risk of respiratory depression for patients with acute or severe asthma and should only be administered in equipped facilities. Taking this drug alongside alcohol or central nervous system depressants can cause severe sedation or respiratory depression; therefore, it's necessary to avoid concurrent use or proceed with extreme caution. Patients with elevated intracranial pressure or head injury may experience worsened symptoms when taking this medication and require caution. This drug can cause psychological and physical dependence; long-term use should be closely monitored for signs of dependency. Patients with impaired liver function are at a higher risk of liver damage and must consult with a doctor before taking this medication. Patients with specific genetic profiles may metabolize this drug rapidly, increasing the risk of respiratory depression, thus requiring dose adjustments and close monitoring. This medication should not be administered to children under 12 years and to pediatric patients under 18 after certain surgeries; adolescents aged 12 to 18 with risk factors should also avoid it. Patients with sleep apnea or hypoxia may experience worsened symptoms after taking this medication, requiring continuous evaluation and possible dose adjustments. Elderly patients or those at risk of hyponatremia should periodically check for the occurrence of hyponatremia while on this medication. This drug has many interactions with specific medications; patients should inform their doctors or pharmacists about any other medications they are taking and monitor for potential adverse reactions while using them together. Women who are pregnant or may become pregnant should carefully consider the effects of this medication on the fetus, and nursing mothers should avoid breastfeeding while taking it for safety. This medication may cause drowsiness or dizziness, hence caution is needed when driving or operating dangerous machinery. In case of an overdose, severe respiratory depression, seizures, or liver damage may occur, so it is crucial to adhere to the prescribed dosage and visit a medical facility immediately in case of overdose. This medication should be stored out of reach of children and should be carefully managed to prevent misuse.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, shedding of skin, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attacks, respiratory issues with coughing and fever, jaundice (yellowing of skin or eyes), profound drowsiness throughout the body, sudden and severe headache, thunderclap headaches, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Decreased appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a tightly sealed container to prevent air and moisture exposure, and it is safest to keep it at room temperature between 1 to 30 degrees Celsius. This will help maintain the medication's effectiveness and prevent degradation.

Appearance

Pale yellow rectangular film-coated tablet

Package unit

Domestic: 30 tablets/bottle, 300 tablets/bottle Export: 100 tablets/bottle