Uniloba Tablet 10mg (Rosuvastatin Calcium)

Adult dosage

Without regard to meals, administer 5 milligrams once daily as the initial dose. The maintenance dose is 10 milligrams once daily; it may be increased up to a maximum of 20 milligrams once daily according to the patient's response at intervals of at least 4 weeks.

Children's dosage

Children aged 10 to 17 years with heterozygous familial hypercholesterolemia are administered 5 milligrams up to 20 milligrams once daily. The dose should be adjusted according to individual treatment targets at intervals of at least 4 weeks.

This medication should not be used in certain patients. For example, patients who are allergic to any component of this drug, those with severe liver dysfunction, patients with muscle disorders, and those who are taking specific medications should avoid treatment. Additionally, women who are pregnant or breastfeeding, as well as women of childbearing potential, must consider pregnancy planning and fetal risks, and should use appropriate contraceptive methods. This medication can affect the liver and muscles, so patients with a history of liver disease, excessive alcohol consumption, and risk factors for myopathy must consult with a physician before use and be monitored carefully. During treatment, if symptoms such as muscle pain, weakness, or fever occur, inform medical personnel immediately, and if necessary, a blood test should be conducted to check for muscle damage. This drug may increase blood sugar levels in some patients; individuals at risk for diabetes should have regular blood glucose checks. Furthermore, this drug can interact with several other medications, so it is essential to inform healthcare providers about any concurrent medications, especially caution is advised when combined with specific antiviral agents, immunosuppressants, antibiotics, and fibrates. Side effects reported in clinical trials and post-marketing studies include headaches, dizziness, dyspepsia, skin rash, muscle pain, and rarely severe side effects such as liver damage or muscle rupture may occur. In case of overdose, as there is no specific antidote, immediate medical attention should be sought for treatment based on symptoms, and monitoring of liver function and muscle enzyme levels should be conducted. Finally, while this medication is unlikely to affect driving or operating machinery, caution is advised as dizziness may occur.

Serious side effects

Allergic reactions including hives and angioedema, chest tightness, difficulty breathing, thrombocytopenia, Stevens-Johnson syndrome, eosinophilia with systemic symptoms drug reaction syndrome (DRESS), jaundice, hepatitis, severe muscle weakness, immune-mediated necrotizing myopathy, rhabdomyolysis, acute renal failure, oliguria, severe edema, severe allergic reactions, severe skin reactions, respiratory issues, liver abnormalities (jaundice), serious

Mild side effects

• Headaches
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rashes
• muscle pain
• weakness
• diarrhea

Store this medication in a tightly closed container to protect from air and moisture. It is best to store it at room temperature between 1°C and 30°C.

Appearance

Pink round film-coated tablet

Package unit

For domestic use - 30 tablets/bottle, for export - 30 tablets/box [(10 tablets/PTP x 3)], for export - 100 tablets/box [(10 tablets/PTP x 10)]