Clarithromycin 250 mg Tablet

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual treatment period is 7～14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In such cases, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Helicobacter pylori eradication in patients with duodenal ulcers: Administer 500mg (potency) of this medicine three times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for an additional 14 days. That is, administer clarithromycin 500mg (potency) per dose three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: Same as adults. Children under 12 years: Use clarithromycin dry syrup.

This medication should not be used in patients with known allergies to certain components. In particular, patients with a history of hypersensitivity reactions to similar classes of antibiotics should not receive this drug. Additionally, it should be avoided in patients with specific heart diseases, severely impaired liver function, and severely decreased kidney function. Women who are pregnant or nursing should also not use this medication. Many drug interactions may occur, so if you are taking other medications, you must consult a physician or pharmacist. If you experience an allergic reaction, severe skin rash, difficulty breathing, or heart irregularities during treatment, discontinue use immediately and consult your healthcare provider. Gastrointestinal symptoms such as abdominal pain, diarrhea, or vomiting should be reported to a doctor if persistent. This medication can affect liver and kidney function, so regular check-ups may be necessary. Elderly patients or those with chronic diseases should take this medication with caution, and dosage adjustments may be required. Do not arbitrarily discontinue or change the dosage and take it accurately as prescribed. Caution is needed when driving or operating machinery, depending on symptoms. In cases of overdose, emergency care such as gastric lavage may be necessary, so seek medical attention immediately.

Shock, anaphylactic symptoms, dyspnea, seizures, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, dyspepsia, abdominal pain, discomfort, belching, diarrhea, oral erosion, epigastric pain, thirst, tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, fecal discoloration, membranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, increased AST, increased ALT, increased γ-GTP, increased LDH, increased ALP, elevated total bilirubin, increased serum creatinine, increased BUN, interstitial nephritis, kidney failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste distortion, hearing loss, paraesthesia, arthralgia, myalgia, olfactory disturbance, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalized pustular dermatosis, muscle cramps, musculoskeletal rigidity, myopathy, elevated serum creatinine levels, elevated serum urea, nephritis, venous inflammation at the injection site, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increased serum alkaline phosphatase, increased serum lactate dehydrogenase, increased INR, prolonged prothrombin time, urine discoloration, vasodilation, cardiac arrest, atrial fibrillation, ectopic beats, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, rash, hyperhidrosis, vesicular dermatitis, papular rash, acne, Henoch-Schonlein purpura

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain storage temperatures between 1 to 30 degrees Celsius to preserve the medication's effectiveness.

Appearance

Yellow oblong film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle