OmegaVen (Purified Fish Oil (High Omega-3 Fatty Acid Content))

Adult dosage

The daily dosage is 1 mL to a maximum of 2 mL/kg body weight for OmegaVen. For purified fish oil, it is 0.1 g to a maximum of 0.2 g/kg body weight. For a patient weighing 70 kg, 70 – 140 mL of OmegaVen will be administered. OmegaVen should be administered alongside other fat emulsions, where its proportion should be 10 - 20% of the total fat intake and the total fat intake should not exceed 2 g/kg.

This medication must only be used under a physician's direction. If severe allergic reactions such as anaphylaxis occur, use must be discontinued immediately. It should not be used in patients with severe bleeding disorders or in life-threatening conditions such as acute myocardial infarction or stroke. It should not be administered to patients with abnormal fat metabolism or severe liver or kidney dysfunction. Due to a lack of experience in using this medication, it should not be given to premature infants, newborns, or children. Do not use this medication if allergic to fish or egg proteins. Cautious use is required in patients with dyslipidemia or uncontrolled diabetes, and those taking anticoagulants. Adverse reactions related to blood coagulation can occur rarely, requiring careful monitoring. During administration, levels of serum triglycerides, blood glucose, electrolytes, and blood counts should be regularly tested. When administering fat emulsions, serum triglyceride levels should be managed to not exceed a certain level, and if adverse reactions appear, the dosage should be adjusted or discontinued. During pregnancy or breastfeeding, it should only be used cautiously when absolutely necessary. In cases of overdose, side effects like fat overload syndrome or metabolic acidosis may occur; therefore, the rate and amount of administration must be strictly controlled. Before use, shake the container well to ensure it is homogeneous, and do not use damaged containers. It is advisable to use infusion equipment that does not contain phthalates, and compatibility should be checked when mixing with other infusions. Care should be taken not to exceed the maximum administration rate, and the duration of administration should not exceed four weeks. Unused medication must be discarded, and storage should be at temperatures below 25 degrees Celsius without freezing.

Serious side effects

Urticaria, anaphylactic reactions, liver abnormalities (including jaundice-related liver dysfunction).

Mild side effects

Fishy taste, prolonged bleeding time, platelet aggregation disorders, abdominal pain, nausea, vomiting, increased body temperature, chills, cold symptoms, fatigue, temporary elevation of liver function tests, hypertriglyceridemia, headache, priapism, skin rash, circulatory disorders (hypertension, hypotension), thrombocytopenia, hemolysis, increased reticulocytes, fever, hyperlipidemia, hyperglycemia.

This medication should be stored in a sealed container to prevent exposure to air or moisture. The storage temperature should be maintained at or below 25 degrees Celsius, taking care not to freeze.

Appearance

A vial containing a white, homogeneous emulsion.

Package unit

50mL/vial x 10, 100mL/vial x 10