Lomefloxacin 100mg Tablet (Lomefloxacin Hydrochloride)

Adult dose

1. Administer lomefloxacin orally at a dose of 100 ～ 200 mg 2 ～ 3 times daily. 2. However, for acute exacerbations of chronic obstructive pulmonary disease, including chronic bronchitis, the usual adult dose of this medicine is 400 mg once daily, taken orally with or without food. The duration of treatment varies depending on the severity of infection, but is usually up to 14 days; treatment should continue for at least 2 days after the symptoms of infection have resolved. 3. Patients with renal impairment 1) Patients with a creatinine clearance of less than 30 mL/min: Administer this medicine as a single initial dose of 400 mg, followed from the next day by 200 mg once daily. 2) Patients on hemodialysis: Administer this medicine as an initial dose of 400 mg, followed from the next day by 200 mg once daily. 3) No dose adjustment is necessary in patients with hepatic impairment; adjust the dose according to renal function.

This medication may cause serious side effects such as tendonitis or tendon rupture, peripheral neuropathy, and central nervous system disorders; if such symptoms occur, discontinuation should be immediate. Patients with myasthenia gravis may experience exacerbation of symptoms, so this drug is not used. It should be used only when no other treatment options are available for acute bacterial sinusitis, acute exacerbations of chronic bronchitis, uncomplicated urinary tract infections, and acute otitis media. Caution should be exercised for elderly patients, those with impaired renal function, and patients taking corticosteroids, as they are at increased risk for tendon rupture. This medication should not be administered to those allergic to quinolone antibiotics, or to children, pregnant women, nursing mothers, or those with a history of tendonitis or tendon rupture. Special caution is advised for patients with a history of epilepsy, renal impairment, aortic disease, or heart valve disease. Various side effects such as allergic reactions, skin rashes, gastrointestinal disturbances, neurological symptoms, blood disorders, and cardiac side effects may occur, so any unusual symptoms should prompt immediate consultation with a healthcare professional. Prolonged exposure to sunlight can cause skin sensitivity, so it is advisable to avoid strong sunlight or artificial UV exposure. Caution is also warranted during driving or operating machinery, as dizziness or drowsiness may occur. Diabetic patients requiring blood sugar control should carefully monitor changes in blood sugar levels and seek immediate treatment if hypoglycemic symptoms arise. There may be drug interactions, so it is important to inform healthcare providers if taking anticoagulants, nonsteroidal anti-inflammatory drugs, antacids, etc. Pregnant or nursing women should not take this medication, and if already in use, breastfeeding should be discontinued. The safety of this drug has not been established in pediatric and adolescent populations. In the event of an overdose, measures such as inducing vomiting or gastric lavage may be required, so strict adherence to prescribed dosages is crucial. During the course of treatment with this medication, it is important to consult with a healthcare professional immediately if any unusual symptoms appear.

• Tendinitis
• tendon rupture
• peripheral neuropathy
• central nervous system effects
• exacerbation of myasthenia gravis
• anaphylactic shock
• anaphylactoid reaction
• rash
• urticaria
• erythema

This medication is sensitive to light and should be stored in a container that does not allow light in. It is also recommended to store it at room temperature between 1 degree and 30 degrees Celsius. This helps maintain the drug's efficacy and safety.

Appearance

Yellow circular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle