Crestor 5 mg (Rosuvastatin Calcium)

Adult dosage

The initial dosage is 5 mg once daily, and if more reduction of LDL cholesterol levels is needed, it can be adjusted to a maintenance dose. The maintenance dose is typically 10 mg once daily, and most patients can be managed on this dosage. The maintenance dose should be appropriately adjusted every 4 weeks or longer intervals based on LDL cholesterol levels, treatment goals, and patient response, and can be increased to a maximum of 20 mg per day.

Children's dosage

The usual dosage range for pediatric patients with homozygous familial hypercholesterolemia (ages 10 to 17 years) is 5 mg to 20 mg once daily. The dosage should be adjusted according to the recommended treatment goals for individual patients.

This medication should not be used in certain patients. For example, patients who are allergic to this medication or have severe liver dysfunction, those with muscle diseases, and women who are pregnant or breastfeeding should not take it. Additionally, caution should be exercised in patients with abnormal liver function or those who consume alcohol in excess, and liver function tests should be repeatedly performed before and during treatment. Patients with hypothyroidism or nephrotic syndrome should prioritize treatment of the underlying conditions. This medication can cause muscle pain or related conditions; therefore, if symptoms such as muscle pain or weakness occur, the physician should be notified immediately. Especially if muscle enzyme levels significantly increase, the medication should be discontinued, and dosing can be adjusted based on improvement of symptoms. This medication can also affect kidney function in some patients; thus, regular kidney function tests are recommended. Asian patients may show higher drug concentrations, necessitating dose adjustment. While this medication is not known to have a significant impact on driving or machine operation ability, dizziness may occur, so caution is advised.

Serious side effects

Hypersensitivity reactions including hives and angioedema, severe myalgia, myopathy, rhabdomyolysis, chest discomfort, difficulty breathing, respiratory distress, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe liver damage, severe muscle weakness, ocular muscle weakness, immune-mediated necrotizing myopathy, acute renal failure, oligoanuria, elevated serum creatinine

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• hematuria
• diarrhea

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained between 1°C to 30°C at room temperature to preserve the medication's effectiveness.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle