Stolaf Tablets 10mg (Lafutidine)

Adult dose

Short-term treatment of gastric ulcers: The usual dose of lafutidine is 10mg orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks, although the time to healing may vary among patients. Short-term treatment of duodenal ulcers: The usual dose of lafutidine is 10mg orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks, although the time to healing may vary among patients. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose of lafutidine is 10mg orally once daily before bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks, although the time to healing may vary among patients. Combination antibiotic therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. Preanesthetic medication: The usual dose of lafutidine is 10mg orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). Treatment of reflux esophagitis: Administer lafutidine 10mg orally twice daily.

This medication should not be used in patients who are allergic to its components. It contains lactose, so patients with genetic conditions such as galactose intolerance, lactase deficiency, or glucose-galactose malabsorption should avoid taking it. Patients with a history of hypersensitivity to the drug, those with liver or kidney function impairment, patients undergoing dialysis, and the elderly should take this medication with caution. This drug can cause severe allergic reactions such as anaphylaxis; if symptoms such as facial pallor, drop in blood pressure, generalized rash, or difficulty breathing occur, stop taking it immediately and consult a healthcare professional. Liver function may be affected, so if there are elevated liver enzymes or symptoms of jaundice, discontinue use and seek medical attention. Serious side effects such as agranulocytosis or thrombocytopenia may occur, so if symptoms such as sore throat, generalized malaise, or fever appear, consult a doctor immediately. Other rare side effects reported include skin rashes, seizures, interstitial nephritis, and rarely cardiac-related symptoms, so caution is advised. Gastrointestinal symptoms may include constipation, diarrhea, nausea, vomiting, abdominal bloating, and loss of appetite, and neurological symptoms such as headache, insomnia, and drowsiness have also been reported. The elderly, having reduced physical function, should be cautious of dosage and intervals, and their condition should be closely monitored. Dialysis patients may experience increased drug concentrations, so they should start with a low dose cautiously. Pregnant women should only take this drug if the benefits outweigh the risks as judged by a doctor, and lactating women are advised not to take it as it may be excreted in breast milk. Safety in children has not been established, so caution is necessary. This drug should be kept out of reach of children and stored in its original container to prevent misuse or deterioration of quality. If a malignant tumor is suspected, testing must be done before taking this medication, and if diagnosed with malignant gastric cancer, use should be discontinued immediately. During treatment, the course of the disease should be monitored carefully, and if ineffective, alternative treatments should be considered. No carcinogenic effects were observed in animal studies; however, hyperplasia of endocrine neurons has been reported at high doses, so recommended dosages should be adhered to.

• Shock
• anaphylaxis symptoms
• facial pallor
• hypotension
• generalized rash
• dyspnea
• hepatic dysfunction
• jaundice
• agranulocytosis
• pharyngodynia

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is advisable to maintain storage temperatures between 1 degree and 30 degrees Celsius in a cool, dry place.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle