Ulpower Set Tablets

Adult dose

Children aged 12 years and older and adults: The dosage should be adjusted based on the level of pain and therapeutic response. A starting dose of 2 tablets is recommended, with subsequent doses spaced at least 6 hours apart, but not exceeding 8 tablets in one day. Administer the effective minimum dose for the shortest duration possible. Avoid prolonged use beyond what is necessary, and if extended treatment becomes necessary due to the nature and severity of the disease, regular monitoring should be undertaken to assess the need for continued administration of this medication. Elderly patients Administer the usual adult dosage. However, for elderly patients over 75 years old, the elimination half-life of tramadol is increased by 17% when taken orally, so doses should be spaced at least 6 hours apart. Patients with renal impairment For moderate renal impairment (creatinine clearance of 10-30 mL/min), extend the dosing interval to 12 hours. Consideration should be given not to recommend use for patients with severe renal impairment (creatinine clearance less than 10 mL/min). As tramadol is removed very slowly during hemodialysis and filtration, there is no need for re-administration of this medication post-dialysis to maintain analgesic effect. Patients with liver impairment For moderate liver impairment, carefully consider extending the dosing interval for administration. This medication should not be given to patients with severe liver impairment.

Child dose

Children aged 12 years and older and adults: The dosage should be adjusted based on the level of pain and therapeutic response. A starting dose of 2 tablets is recommended, with subsequent doses spaced at least 6 hours apart, but not exceeding 8 tablets in one day.

This medication can pose a risk of liver damage if taken by individuals who regularly consume more than three alcoholic drinks a day, so it is essential to consult a doctor or pharmacist before use. Acetaminophen, one of the ingredients in this medication, can rarely cause serious skin reactions; if skin rashes or hypersensitivity reactions occur, discontinue use immediately. The main ingredient, tramadol, may increase the risk of seizures when doses exceed the recommended amount, and the risk is heightened when used in combination with certain antidepressants or narcotics, so caution is advised. Rarely, life-threatening allergic reactions, such as anaphylaxis, may occur while taking this medication; if any unusual symptoms appear, contact healthcare professionals immediately. In patients with acute and severe bronchial asthma, this medication may cause life-threatening respiratory depression, so it should only be administered in a facility equipped with proper medical equipment. Taking this medication with alcohol or central nervous system depressants may increase the risk of severe sedation, respiratory depression, coma, and death; thus, combinations should be avoided or used with utmost caution. Patients with elevated intracranial pressure or head injuries may experience worsening of symptoms due to the respiratory depressant effects of this medication, so caution is necessary. Tramadol can cause dependence similar to morphine; therefore, monitoring for the development of substance dependence is important during long-term use. Acetaminophen can lead to liver damage, so patients with impaired liver function must consult with a doctor prior to use. Patients who are ultra-rapid metabolizers of CYP2D6 may have increased serum active metabolite concentrations when taking this medication, raising the risk of respiratory depression, so dose adjustment and careful monitoring are necessary. This medication should not be given to children under 12 years of age or children after certain surgeries, and adolescents aged 12 to 18 should avoid use in the presence of particular risk factors. Patients with sleep apnea should consider dose adjustments or discontinuation as this medication can exacerbate symptoms. This medication may cause hyponatremia; therefore, it is advisable for elderly patients or those with risk factors to regularly check their serum sodium levels. Patients with allergies to the ingredients in this medication, central nervous system drug dependence, severe respiratory depression, head injuries, or currently taking MAO inhibitors should not use this medication. This medication should not be administered to patients with severe liver, kidney, or heart dysfunction, nursing mothers, children under 12 years of age, or certain asthma patients. Caution is advised when used in combination with narcotic analgesics, antidepressants, sedatives, etc., as the risk of seizures and respiratory depression may increase. Sudden discontinuation can lead to withdrawal symptoms; therefore, it is safest to taper the dose gradually as directed by a doctor. This medication may cause drowsiness or dizziness when driving or operating machinery, so caution is required. In cases of overdose, there is a risk of severe respiratory depression, seizures, and liver damage; therefore, strict adherence to the prescribed dose is mandatory, and in case of emergencies, contact a medical institution immediately. This medication should be stored in a secure location out of reach of children, and it should be carefully managed to prevent misuse or abuse.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain of mucous membranes in the mouth/eyes, acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), generalized.

Mild side effects

• Decreased appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a tightly sealed container that allows for proper air circulation, ideally at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness for an extended period.

Appearance

Pale yellow rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle