Nephcom Injection (Nepafenac Hydrochloride)

Adult administration

Administer 20 mg of nefopam hydrochloride per dose by intramuscular or intravenous injection. If necessary, repeat every 6 hours, not exceeding 120 mg per day. Administer intravenous injections slowly over at least 15 minutes. After administration, it is preferable for the patient to lie still and rest for 15-20 minutes. When added to an infusion solution such as an electrolyte or glucose solution, administer 30 mg over 4 hours or 40 mg over 6-8 hours, in proportion to the administration time. It is recommended that this medicine not be mixed with other medicines for injection. The dosage may be adjusted according to age and symptoms.

This medicine is an ampoule injection, and care must be taken when opening the container as glass shards may mix in. It should not be used by patients with epilepsy, myocardial infarction, those taking MAO inhibitors, individuals allergic to this medication or its components, children under 15 years of age, patients with a history of seizures, individuals with urinary difficulties due to urethra or prostate issues, and those with closed-angle glaucoma. Elderly patients, women who are pregnant or breastfeeding, and patients taking anticholinergic medications should use this medication with caution. This medication may cause decreased appetite, nausea, vomiting, drowsiness, excessive sweating, dizziness, increased heart rate, dry mouth or urinary retention, injection site pain, headache, blurred vision, fatigue, nervousness, sleep disturbances, hallucinations, and other symptoms. These side effects usually depend on the dose of the medication and may gradually disappear with repeated administration. While this medication helps alleviate symptoms in cases of inflammation, pain, or fever, it is not a treatment for the underlying cause. Therefore, when possible, definitive treatment of the cause should be conducted alongside. This medication should be used together with appropriate antibiotics or antifungal agents to treat infections causing inflammation, and the patient's condition should be closely monitored. For elderly patients, it should be administered cautiously at a minimum dose and special attention should be given to the occurrence of side effects. Patients with liver or kidney dysfunction may have altered metabolism and excretion of this medication, thus requiring careful monitoring. As this medication may cause drowsiness or decreased concentration, it is advisable to avoid driving or operating machinery. When used with other analgesics or certain medications, side effects may be exacerbated, so consultation with a healthcare professional is necessary. Pregnant or breastfeeding women are advised not to take this medication. Safety and efficacy have not been established in children under 15 years of age, so it should not be used. It is not recommended for elderly patients due to potential anticholinergic side effects. If an overdose occurs, promptly consult a doctor or pharmacist and closely monitor cardiac and respiratory status. It is advisable not to mix this medication with other drugs for injection. When stored, keep out of reach of children, avoid direct sunlight, and store in a cool, dry place.

• Loss of appetite
• gastrointestinal disturbances
• nausea
• drowsiness
• vomiting
• excessive sweating
• dizziness
• tachycardia
• palpitations
• thirst

This medication should be stored in a sealed container to prevent air or moisture from entering, preferably at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will help maintain the medication's efficacy for a longer period.

Appearance

A transparent glass ampoule containing a colorless, transparent liquid

Package unit

2mL × 100 ampoules, 5mL × 50 ampoules