Cretrol Tablets 10/20 mg

Adult dose

This medication is administered once daily without regard to meals. The dosage range is 10/5 mg to 10/20 mg per day. The initial recommended dose is 10/5 mg once daily. For patients requiring a greater reduction in LDL-C, the dose may be adjusted. After starting treatment or adjusting the dosage, lipid levels should be checked at least 4 weeks apart, and adjustments should be made accordingly.

This medication helps lower blood cholesterol levels by inhibiting cholesterol synthesis in the liver. If symptoms such as muscle pain or weakness, fatigue, or fever occur during the use of this medication, the patient should inform their doctor immediately, as muscle damage may occur. Severe muscle damage can develop into a serious condition called rhabdomyolysis, which can lead to a rapid decline in kidney function; hence, careful monitoring is essential. Since this medication can affect liver function, liver function tests should be performed before starting treatment, and regular liver function tests should be conducted during treatment. Women who are pregnant or may become pregnant, and nursing mothers should not take this medication due to potential harm to the fetus or infant. This medication should not be administered to individuals with certain genetic disorders, severe liver disease, kidney disorders, or muscle diseases. Also, interactions may occur when used with other medications, so any current medications should be disclosed to a doctor or pharmacist. It is advisable to avoid alcohol while taking this medication, especially in individuals with a history of liver disease. Elderly patients or those with impaired kidney function are at higher risk of muscle injury and should take the medication under strict medical supervision. The safety and efficacy of this medication have not been established in children and is not recommended for use in this population. Patients should contact healthcare personnel immediately if they experience severe skin rashes, itching, swelling, or difficulty breathing during treatment. There is no specific antidote for overdose; treatment should be symptomatic, and liver and muscle function tests may be necessary.

Serious side effects

Urticaria, swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizure, confusion of consciousness, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• muscle pain
• edema
• elevated blood bilirubin
• itching
• dermatitis

This medication should be stored in a tightly closed container to protect it from air and moisture. Maintain storage temperatures between 1°C and 30°C.

Appearance

White to almost white round film-coated tablets

Package unit

Blister - 30 tablets/blister [10 tablets/blister × 3], Bottle - 30 tablets/bottle, Bottle - 300 tablets/bottle