Ezrosu 10/20 mg

Adult dose

This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, doses of 10/5 mg to 10/20 mg once daily are appropriate, with an initial recommended dose of 10/5 mg. Doses can be adjusted for patients needing greater LDL cholesterol reduction. Blood lipid levels should be checked at intervals of more than 4 weeks after starting treatment or adjusting the dose before making changes.

This medication may rarely cause serious side effects related to muscle damage that can impact renal function in patients with certain muscle diseases or severely impaired kidney function. Therefore, patients with severe infections, hypotension, major surgery or trauma, or severe metabolic disorders may need to temporarily discontinue or stop taking this medication. Patients with allergies to the active ingredients or components of this medication, those with severe liver dysfunction, muscle disease, those on concomitant immunosuppressants, severely impaired kidney function, pregnant or potentially pregnant women, and nursing mothers should not take this medication. Additionally, patients with a family history of muscle disease, hypothyroidism, alcohol abuse, or those on certain medications should not take this medication in high doses. Patients with genetic metabolic disorders like lactose intolerance should also avoid this medication. Alcohol abusers, those with a history of liver disease, impaired kidney function, elderly patients, patients prone to myopathy, and those taking certain medications should use this medication cautiously. If muscle pain, cramps, or weakness occur during treatment, inform a doctor immediately and undergo evaluation; in severe cases, discontinue the medication. Liver function abnormalities may also occur, so liver function tests should be conducted before and during treatment, and if abnormalities are found, the medication dosage should be adjusted or discontinued. This medication can raise blood sugar levels; however, since the cardiovascular risk reduction effect is greater, it is important to continue using it alongside blood sugar management. This medication may interact with other drugs, so if taking other medications, patients must inform their doctor or pharmacist, particularly with anticoagulants, certain antibiotics, immunosuppressants, and fibrate drugs. Pregnant or nursing women should not take this medication as it may pose a risk to the fetus or infant, and women of childbearing age should use appropriate contraception while taking it. The safety of this medication in children and adolescents has not been sufficiently established, so its use is not recommended. This medication may cause symptoms such as dizziness, so caution is needed when driving or operating machinery. In cases of overdose, as there is no specific antidote, seek appropriate treatment and medical evaluation immediately.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urinary issues.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• nasopharyngitis
• ALT increase
• AST increase
• ALP increase
• abnormal liver function tests

This medication is sensitive to air and moisture, so it must be tightly closed and stored in a sealed state. The suitable storage temperature is between 1 and 30 degrees Celsius at room temperature, avoiding extremely hot or cold places.

Appearance

Pink, oval film-coated tablet

Package unit

30 tablets/bottle, 30 tablets/box [(10 tablets/PTP x 3)]