Medication info
Jardiance Duo Tablet 12.5/1000 milligrams

Jardiance Duo Tablet 12.5/1000 milligrams

Prescription medicationTablet경구
Ingredient · strength
Empagliflozin›12.5mg / 1 tabletMetformin Hydrochloride›1000mg / 1 tablet
Manufacturer / importer
한국베링거인겔하임(주)
Appearance
Brownish-purple, bilaterally convex, oval film-coated tablet
Packaging
60 tablets/box [10 tablets/PTP × 6 packs]
Approval status
Active

MFDS item code 201600390 · Approved 2016.01.21 · Insurance code 653501520

Summary

Main use
Blood sugar control and prevention of cardiovascular events in adult patients with type 2 diabetes
Who takes it
Adults
Adult dose
The recommended dosage of this medication is 1 tablet per dose, twice a day. In cases where blood glucose control is insufficient when using metformin alone or in combination with other medications such as insulin, empagliflozin 5 mg is administered twice a day, and if tolerance is good and additional blood sugar control is needed, the dose of empagliflozin may be increased up to a total of 25 mg per day. This medication should be taken with meals, and if a dose is missed, one should take it as soon as they remember; however, do not take a double dose at once.

Ingredients

Importer
한국베링거인겔하임(주)

Efficacy & effects

Blood sugar control and prevention of cardiovascular events in adult patients with type 2 diabetes

  • Failure in blood sugar control
  • type 2 diabetes
  • cardiovascular disease
  • cardiovascular events
View approved original text

This medication is used to assist in the improvement of blood sugar control in adult patients with type 2 diabetes who are using empagliflozin and metformin together, in conjunction with diet and exercise regimen. Particularly in adult patients with type 2 diabetes where blood sugar is not adequately controlled, and who have cardiovascular disease, caution regarding the occurrence of cardiovascular events is required; therefore, it is important to refer to the guidelines from a specialist. This medication effectively controls blood sugar and helps in the overall health management of the patient.

How to take

Adult dose

The recommended dosage of this medication is 1 tablet per dose, twice a day. In cases where blood glucose control is insufficient when using metformin alone or in combination with other medications such as insulin, empagliflozin 5 mg is administered twice a day, and if tolerance is good and additional blood sugar control is needed, the dose of empagliflozin may be increased up to a total of 25 mg per day. This medication should be taken with meals, and if a dose is missed, one should take it as soon as they remember; however, do not take a double dose at once.

Precautions

This medication contains components that help lower blood sugar levels. However, there is a risk of a rare side effect called severe lactic acidosis, and if symptoms occur, immediate consultation with healthcare professionals is necessary. There may be an increased risk of hypoglycemia when used in conjunction with other diabetes treatments. This medication should not be used in patients with severely impaired kidney function, acute kidney issues, severe infections, heart failure, or acute myocardial infarction. If undergoing tests using iodinated contrast agents, this medication should be discontinued for a period before and after the examination. It is safest for pregnant women or those who may become pregnant, as well as nursing mothers, not to take this medication. Elderly patients or those with slightly impaired kidney function should regularly monitor their kidney function and adjust the dosage accordingly. There may be side effects such as gastrointestinal disturbances, urinary tract infections, genital infections, increased urination, hypoglycemia, and it's important to inform healthcare professionals if symptoms occur. Patients at risk of fluid loss should be cautious with fluid intake to prevent dehydration, and may temporarily discontinue the medication if necessary. It is also advised to avoid alcohol consumption during the course of this medication, and if any unusual symptoms or discomfort occur, immediate consultation with healthcare professionals is necessary. Additionally, this medication may interact with certain medications, so it is important to inform if there are other medications being taken. Finally, this medication is not recommended for children or adolescents under the age of 18.

Side effects and when to seek care immediately

Serious side effects

  • Urticaria
  • angioedema
  • necrotizing fasciitis of the perineum
  • urosepsis
  • pyelonephritis
  • lactic acidosis
  • ketoacidosis
  • cerebral infarction
  • myocardial infarction
  • acute renal injury
Show 15 more
  • acute cholecystitis
  • autoimmune hepatitis
  • cholelithiasis
  • acute pyelonephritis
  • sepsis
  • septic shock
  • acute myocardial infarction
  • cardiovascular collapse
  • acute congestive heart failure
  • heart failure
  • severe allergic reactions
  • severe skin reactions
  • respiratory problems
  • liver abnormalities (jaundice)
  • severe

Mild side effects

  • Hypoglycemia
  • urinary tract infection
  • genital infection
  • increased urination
  • nausea
  • vomiting
  • diarrhea
  • abdominal pain
  • loss of appetite
  • constipation
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  • abnormal liver function tests
  • hepatitis
  • altered taste
  • itching
  • rash
  • erythema
  • increased blood creatinine
  • difficulty urinating
  • thirst
  • reduced and deficient Vitamin B12
  • headache
  • dizziness
  • insomnia
  • decreased appetite
  • hyperglycemia
  • hyponatremia
  • weight loss
  • anxiety
  • chest discomfort
  • chest pain
  • weakness
  • facial swelling
  • edema

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Brownish-purple, bilaterally convex, oval film-coated tablet

Package unit

60 tablets/box [10 tablets/PTP × 6 packs]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.