Conblox Tablet 10 mg (Bisoprolol Fumarate)

Adult dose

Administer orally once a day either on an empty stomach in the morning or during breakfast without chewing, along with a beverage. 1. Hypertension, angina: Administer 5-10 mg of bisoprolol fumarate orally once daily. For mild cases, 5 mg is sufficient, while for severe cases, 10 mg is used. In special cases, a maximum of 20 mg may be administered per day. 2. Stable chronic heart failure: Start with an initial dose of 1.25 mg, observing tolerability over time, and after 2 weeks or more, the dose may be gradually increased.

Child dose

Experience in using this medication for children is lacking, so administration is not recommended.

This medication should be used with caution as there is no experience in using it for patients with certain diseases or conditions among heart failure patients. Patients with bronchial asthma or chronic obstructive pulmonary disease should use it together with bronchodilators, and in asthma patients, increased airway resistance may necessitate dosage adjustments. Like other beta blockers, this medication may increase the risk of allergic reactions, and adrenaline treatment may not always be effective. Patients with psoriasis or a history of psoriasis should carefully consider the risks and benefits of using this medication. Patients with pheochromocytoma should use this medication after administration of alpha blockers, and symptoms of hyperthyroidism may be masked by this medication. Regular health monitoring is required during the initial administration, and sudden discontinuation may worsen heart conditions, so the dosage should be gradually decreased. This medication should not be used in patients with diabetic ketoacidosis, severe bradycardia, cardiogenic shock, acute heart failure, and certain other cardiac and metabolic diseases. Pregnant women or women who may become pregnant should not take this medication, and it is recommended to avoid use during breastfeeding. Safety for pediatric patients has not been established, so use is not recommended. Elderly patients should start with a low dose and use cautiously, and dosage adjustments may be necessary for those with impaired liver or kidney function. This medication may affect driving or operating machinery, so caution is required, especially at the beginning of treatment or when changing medications. In case of overdose, symptoms such as bradycardia, hypotension, bronchospasm may occur, and in such cases, immediate medical treatment should be sought. This medication can interact with several other drugs, so it is essential to inform healthcare providers of any other medications being taken. Long-term use requires regular monitoring of heart function as well as liver and kidney function, and if any abnormal symptoms occur, immediate consultation with a doctor is advised.

Serious side effects

Severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness), severe skin reactions (severe rash with fever, blisters, skin peeling, pain in the mouth/eyes), respiratory problems (shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanying respiratory abnormalities), liver abnormalities (yellowing of the skin or eyes, generalized fatigue), serious neurological symptoms (sudden and severe reactions)

Mild side effects

• Bradycardia
• worsening of heart failure
• cold or numb extremities
• hypotension
• dizziness
• headache
• nausea
• vomiting
• diarrhea
• constipation

This medication must be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Dark yellow film-coated tablets in a heart shape with a break line on one side and bulging on both sides.

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle