Alpiclarry Tablets 250mg (Clarithromycin)

Adult dosage

○ Adults: The usual dose is 250mg (potency) of clarithromycin per dose twice daily. For severe infections, administer 500mg (potency) per dose twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer this medicine to such patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine per dose twice daily. In this case, it must be used in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: For 14 days, administer 500mg (potency) of this medicine three times daily in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose three times daily for 14 days (1～14 days), and administer omeprazole 40mg once daily for 28 days (1～28 days).

Children's dosage

○ Children aged 12 years and older: Same as adults ○ Children under 12 years: Use clarithromycin dry syrup.

This medication should not be administered to specific patients. Individuals who are allergic to any components of this medication, or have shown hypersensitivity to antibiotics of a similar class, should not use it. Additionally, it should not be administered to patients with severe heart disease, severe liver dysfunction, pregnant or nursing women, or individuals with certain neurological infections. This medication may be affected by liver and kidney function; hence, patients with liver dysfunction or renal failure should use it with caution. Patients with heart disease, elderly patients, or those currently taking other antibiotics should also be administered with care. During treatment, various adverse reactions may occur, including allergic reactions, digestive issues, skin rashes, liver function abnormalities, kidney function decline, central nervous system symptoms, etc. If any of these symptoms occur, consult a physician immediately. This medication may interact with other drugs, so it is essential to inform your doctor or pharmacist about any medications you are currently taking. Caution is particularly required when taken with cardiovascular drugs, drugs that affect liver metabolism, hypoglycemic agents, immune suppressants, etc. It is generally safer to avoid this medication during pregnancy or lactation; if it must be used, consultation with a healthcare professional is necessary. Dosage adjustments and caution are also needed for children and the elderly; specifically, the safety and efficacy of this medication in children under 12 years old have not been sufficiently established. In cases of overdose, gastrointestinal disturbances, psychiatric symptoms, and electrolyte imbalances may occur, requiring immediate medical attention. When using this medication, it is crucial to conduct sensitivity tests against infection-causing bacteria to prevent the emergence of resistant strains and to take it only for the necessary duration. Additionally, persistent diarrhea or abdominal pain may indicate severe side effects such as colitis, which necessitates an immediate hospital visit. Lastly, caution is needed while driving or operating machinery during the course of this medication, as dizziness or confusion may occur.

• Shock
• anaphylactic symptoms
• dyspnea
• convulsions
• flushing
• rash
• itching
• urticaria
• skin erythema
• angioedema

This medication is sensitive to light, so it should be stored away from direct sunlight. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius, and it is important to keep it in a sealed container to prevent air ingress.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle