Sitaglomet Metformin Tablets 50/1000 mg

Adult dosage

This medication is generally taken twice daily with food, and the dose is gradually increased to reduce gastrointestinal adverse reactions caused by metformin. 1. For patients who are not currently treated with metformin: Start with this drug at 50/500 mg, taking one tablet twice daily, and may increase to 50/1000 mg. 2. For patients currently receiving metformin: Start the dosage with sitagliptin at 50 mg twice daily.

This medication is composed of two ingredients: sitagliptin and metformin, and is used for blood sugar control in patients with type 2 diabetes. Firstly, during the use of this medication, severe allergic reactions such as skin rash, swelling, or difficulty breathing may occur. If such symptoms arise, stop taking the medication immediately and consult a doctor. Also, acute pancreatitis, a serious inflammation of the pancreas, may occur, so if symptoms such as abdominal pain, vomiting, or fever appear, inform a healthcare professional immediately. The metformin in this drug can cause lactic acidosis, a rare but potentially fatal metabolic condition. Therefore, patients with impaired kidney function, liver dysfunction, severe infections, or dehydration should not take this medication. Specifically, if kidney function is moderately impaired or if there are acute conditions such as heart failure, acute myocardial infarction, or sepsis, this drug should not be used. Administration should also be suspended before and after examinations using iodinated contrast agents. This medication has not been confirmed safe for use in pregnant or breastfeeding women, nor in children and adolescents under 18 years of age. While taking this medication, regular kidney function tests should be conducted to monitor kidney status, and alcohol consumption should be avoided as it may increase the risk of lactic acidosis. The risk of hypoglycemia may increase when taken with other blood sugar-lowering medications, so patients should be cautious of hypoglycemic symptoms and may need adjustments in dosages of those medications as necessary. Additionally, irregular meals, vigorous exercise, and nutritional imbalances can increase the risk of hypoglycemia or lactic acidosis, so caution is advised. Severe joint pain, skin conditions, and liver dysfunction have been reported as side effects, so if any abnormal symptoms occur, inform a healthcare professional immediately. After surgery, the use of this medication should be suspended for a certain period, and it is important for patients and their families to receive adequate education regarding the medication's side effects and precautions.

Serious side effects

Hives, severe swelling (angioedema), tightness in the chest, difficulty breathing, anaphylaxis, Stevens-Johnson syndrome (severe skin reactions), acute pancreatitis, acute renal failure, severe joint pain, blistering similar to pemphigus, thrombocytopenia, acute renal failure, dyspnea, unstable angina, severe hypoglycemia, severe allergic reactions, severe swelling or urinary abnormalities

Mild side effects

• Diarrhea
• upper respiratory tract infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a tightly closed container to prevent exposure to air and kept at room temperature between 1 to 30 degrees Celsius. Proper storage can help maintain the efficacy of the medication for a longer period.

Appearance

Red oval film-coated tablet

Package unit

28 tablets (14 tablets/PTP × 2)