Lobide Tablet 20mg (Rosuvastatin Calcium)

Adult dosage

Administer 5 milligrams once daily as an initial dose at any time during the day, regardless of meals. For patients requiring more significant LDL cholesterol reduction, a maintenance dose of 10 milligrams once daily can be given, and this can be adjusted based on the patient’s response at intervals of at least 4 weeks. Dosing may be increased to a maximum of 20 milligrams per day.

Children's dosage

For pediatric patients aged 10 to 17 years with heterozygous familial hypercholesterolemia, administer a once daily dose between 5 milligrams and 20 milligrams. The dosage should be adjusted according to the individual patient’s treatment goals with intervals of at least 4 weeks.

This medication should not be used in certain patients. For instance, those who are allergic to this drug, those with severely impaired liver function, those with muscle diseases, those with severely compromised kidney function, and women who are pregnant or nursing should not take this drug. Additionally, this medication should be used with caution in individuals who consume excessive alcohol or have a history of liver disease, and regular liver function tests should be conducted. If symptoms of muscle pain or weakness occur, the physician should be notified immediately, and in severe cases, the medication should be discontinued. This medication may increase blood sugar levels in some patients, raising the risk of diabetes; therefore, patients at risk for diabetes should undergo regular blood sugar monitoring. This medication may interact with other drugs, so it is essential to inform the physician or pharmacist of any other medications being taken, especially certain antibiotics, antifungals, immunosuppressants, and fibrate class drugs, as the risk of muscle-related side effects may increase when taken together. Women of childbearing potential should use appropriate contraception and should not take this medication while pregnant. Nursing women should also avoid taking this medication for safety. In the event of an overdose, there are no specific antidotes, so treatment should be symptomatic, and liver function and muscle enzyme levels should be monitored. Dizziness may occur during driving or operating machinery, so caution is advisable. This medication may cause serious allergic reactions in the skin; if symptoms such as rash or itching occur, the medication should be stopped immediately, and a physician should be consulted.

Serious side effects

Hives, allergic reactions including angioedema, severe muscle weakness, ophthalmoplegia, myopathy, rhabdomyolysis, acute kidney injury, anuria, thrombocytopenia, elevated serum creatinine, severe rash with fever, blistering, skin peeling, oral/ocular mucosal pain, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, liver failure, severe allergic reactions, severe

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• diarrhea
• syncope

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is recommended to store it at room temperature between 1 degree and 30 degrees Celsius. By storing it this way, the effectiveness of the medication can be maintained, and it can be used safely.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle