Rovide 5 mg (Rosuvastatin Calcium)

Adult dosage

The initial dose is 5 milligrams once daily, and if greater reduction in LDL cholesterol is needed, the maintenance dose can be adjusted. The maintenance dose is usually 10 milligrams once daily, and most patients are controlled on this dose. The maintenance dose should be adjusted appropriately every four weeks or more based on LDL cholesterol levels, treatment goals, and patient response, with a maximum increase to 20 milligrams daily.

Children's dosage

The usual dosage range for pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17 years) is 5 milligrams to 20 milligrams once daily. The dosage should be adjusted according to the recommended therapeutic goals for each individual patient.

This medication should not be used in certain patients. For example, patients allergic to any component of this medication, those with severe liver disease, muscular disorders, and severe renal impairment should not take this medication. Caution is also required for women who are pregnant, nursing, or of childbearing age who are not using effective contraception before taking this medication. Furthermore, high-dose administration is contraindicated for patients at high risk of muscle disease. It is important to periodically check liver function and muscle condition while taking this medication. Patients with a history of liver disease or those who consume excessive alcohol require more careful monitoring. If symptoms such as muscle pain, weakness, or cramps occur, the physician should be notified immediately for examination. This medication may interact with some other drugs, so if taking other medications, it's essential to inform the physician or pharmacist. In particular, concomitant use with certain antibiotics, antifungals, immunosuppressants, and fibrate drugs may increase the risk of muscle side effects. It is safest not to use this medication during pregnancy or breastfeeding, and women of childbearing age should undergo appropriate contraception. In cases of overdose, there is no specific antidote, so treatment should be symptomatic, monitoring liver function and muscle enzyme levels. Dizziness may occur, so caution is required while driving or operating machinery. Lastly, this medication may have higher blood concentrations in Asians, so dose adjustment may be necessary.

Serious side effects

Hives, angioedema, chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe muscle weakness, ophthalmoplegia, rhabdomyolysis, immune-mediated necrotizing myopathy, acute renal failure, oliguria, hyperbilirubinemia, hepatic failure, thrombocytopenia, polyneuropathy, severe skin reactions, severe allergic reactions, severe edema

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• asthenia
• diarrhea

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, in a temperature range of 1 to 30 degrees Celsius. This helps maintain the effectiveness of the medication and prevent deterioration.

Appearance

Yellow, round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle