Cefusil Tablet 250mg (Cefuroxime Axetil)

Adult dose

For optimal absorption, this medicine should be taken after meals. Adults 1) Most infections: Administer 250mg per dose, 2 times daily. 2) Severe lower respiratory tract infections, pneumonia, severe infections, or suspected infections caused by less susceptible organisms: Administer 500mg per dose, 2 times daily. 3) Urinary tract infections: Administer 250mg per dose, 2 times daily. 4) Uncomplicated gonorrhea: Administer 1g as a single dose. 5) Lyme disease: Administer 500mg per dose, 2 times daily for 14 days (10~21 days). 3. Patients with renal impairment Cefuroxime is excreted primarily by the kidneys. In patients with markedly impaired renal function, reducing the dose of cefuroxime as below is recommended to compensate for delayed excretion. ≥ 30 mL/min/1.73m2: No dosage adjustment required (standard dose: 125mg-500mg per dose, 2 times daily) 10 - 29 mL/min/1.73m2: Administer a standard single dose every 24 hours < 10 mL/min/1.73m2: Administer a standard single dose every 48 hours Patients undergoing hemodialysis: Administer an additional standard single dose at the end of each dialysis session For the treatment of infections caused by Streptococcus pyogenes (Group A beta-hemolytic), this medicine should be administered for 7~10 days.

Child dose

Children aged 12 years and older, most infections: Administer 250mg per dose, 2 times daily. Children aged 12 years and older, severe lower respiratory tract infections, pneumonia, severe infections, or suspected infections caused by less susceptible organisms: Administer 500mg per dose, 2 times daily. Children aged 12 years and older, urinary tract infections: Administer 250mg per dose, 2 times daily. Children aged 12 years and older, uncomplicated gonorrhea: Administer 1g as a single dose. Children aged 12 years and older, Lyme disease: Administer 500mg per dose, 2 times daily for 14 days (10~21 days). Infants and children under 12 years, most infections: Administer 125mg per dose, 2 times daily. Children aged 2 years and older, otitis media or severe infections: Administer 250mg per dose, 2 times daily. Infants and children under 12 years, Lyme disease: Administer 250mg per dose, 2 times daily for 14 days (10~21 days). There is insufficient experience with use in infants under 3 months of age. This medicine should not be divided and is therefore not suitable for treating patients who cannot swallow tablets, such as young children and infants.

This drug should not be used in patients with hypersensitivity to cephalosporin antibiotics. Patients with a history of hypersensitivity to penicillin or other beta-lactam antibiotics, those with allergic constitution, severe renal impairment, patients who have difficulty taking orally or the elderly should be administered with caution. While taking this medication, a variety of adverse reactions may occur, from mild side effects to rare but serious skin reactions, so careful observation is necessary. Particularly, headaches, dizziness, gastrointestinal disturbances, rashes, hives, liver function abnormalities, and kidney function abnormalities may occur, so if symptoms worsen, immediate consultation with a healthcare professional is necessary. Long-term use may lead to excessive growth of Candida or other non-susceptible bacteria, so symptoms should be closely monitored. If diarrhea or abdominal pain persists or worsens, the possibility of pseudomembranous colitis should be considered, and appropriate action should be taken immediately, including stopping the treatment. This medication may cause dizziness, so care should be taken during driving or operating machinery. If severe skin reactions occur, treatment should be stopped immediately, and alternative therapy should be sought; it should not be used again thereafter. This drug may interact with other medications, so patients taking diuretics, aminoglycoside antibiotics, probenecid, antacids, etc., should inform their healthcare provider. Women who are pregnant or breastfeeding should use this medication with caution, and women who might become pregnant should carefully consider the risks and benefits of treatment. Safety has not been established for infants under three months of age, and for pediatric patients, using a dry syrup is recommended due to the bitter taste. The elderly may experience side effects more easily due to decreased physiological function, so dosage and administration should be adjusted, and they should be observed closely. This medication may affect the results of some clinical tests, so inform your healthcare provider about taking it during tests. Excessive doses can cause serious side effects such as seizures; caution is required, and blood dialysis or peritoneal dialysis can reduce drug concentrations. Finally, this medication should be kept out of reach of children, stored in its original container to prevent degradation or misuse.

• Candidiasis hyperproliferation
• eosinophilia
• positive Coombs test
• thrombocytopenia
• leukopenia
• granulocytopenia
• erythrocytopenia
• hemoglobin decrease
• hematocrit decrease
• hemolytic anemia

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Storing it this way will maintain the effectiveness of the drug for a long time.

Appearance

White rectangular film-coated tablet

Package unit

50 tablets (10 tablets/PTP x 5)