Medication info
Megaseculer Capsule (Cefaclor Hydrate)

Megaseculer Capsule (Cefaclor Hydrate)

Prescription medicationHard capsule경구
Ingredient · strength
Cefaclor Hydrate›250mg / 1 capsule
Manufacturer / importer
(주)엘앤씨바이오
Appearance
Upper part is blue opaque and lower part is white opaque hard capsule filled with light yellow powder
Packaging
30 capsules/bottle, 300 capsules/bottle
Approval status
Active

MFDS item code 201507396 · Approved 2015.10.27 · Insurance code 060500040

Summary

Main use
Treatment of otitis media, respiratory infections (pneumonia, pharyngitis) and urinary tract infections (pyelonephritis, cystitis)
Who takes it
Adults · Children
Adult dose
For cefaclor hydrate, take 250 mg (potency) by mouth every 8 hours. In cases of severe infections (such as pneumonia) or infections with low sensitivity, the dose can be doubled. For acute gonococcal urethritis, this drug 3 g and probenecid 1 g may be administered as a single combined dose.
Child dose
Administer 20 mg/kg (potency) every 8 hours, divided as needed. For severe infections, otitis media, and infections with low sensitivity, a dose of 40 mg/kg (potency) can be administered per day, with a maximum dose of

Ingredients

Manufacturer
(주)엘앤씨바이오

Efficacy & effects

Treatment of otitis media, respiratory infections (pneumonia, pharyngitis) and urinary tract infections (pyelonephritis, cystitis)

  • Otitis media
  • pneumonia
  • pharyngitis
  • tonsillitis
  • bronchitis
  • pyelonephritis
  • cystitis
  • gonococcal urethritis
  • boils
  • abscesses
  • folliculitis
  • soft tissue infections
View approved original text

This drug is effective against various bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus, and Escherichia coli. It is mainly used for respiratory infections like otitis media, pneumonia, pharyngitis, tonsillitis, and bronchitis. It is also helpful in the treatment of urinary infections like pyelonephritis, cystitis, and gonococcal urethritis. It is effective in treating skin infections including boils, abscesses, folliculitis, soft tissue infections, and wound infections. Thus, it is effective against various bacterial infections in multiple areas and is used to improve infectious diseases.

How to take

Adult dose

For cefaclor hydrate, take 250 mg (potency) by mouth every 8 hours. In cases of severe infections (such as pneumonia) or infections with low sensitivity, the dose can be doubled. For acute gonococcal urethritis, this drug 3 g and probenecid 1 g may be administered as a single combined dose.

Child dose

Administer 20 mg/kg (potency) every 8 hours, divided as needed. For severe infections, otitis media, and infections with low sensitivity, a dose of 40 mg/kg (potency) can be administered per day, with a maximum dose of

Precautions

This drug is an antibiotic that kills bacteria by binding to specific proteins and disrupting bacterial cell wall synthesis. Before using this drug, it should not be administered if there is an allergy to this drug or to cephalosporin antibiotics, or if there has been a history of severe allergic reactions or shock due to this drug. Additionally, patients with genetic disorders that prevent lactose breakdown should not take this drug. Patients allergic to penicillin antibiotics, those with asthma or a tendency for frequent skin allergies, patients with severely impaired kidney function, those unable to take oral medications, elderly patients, and those with a history of gastrointestinal disorders should exercise caution when using this drug. During the course of this medication, rare side effects such as shock, anaphylaxis, severe skin conditions, blood disorders, liver or kidney function impairment, gastritis, pneumonia, or neurological abnormalities may occur, so if symptoms appear, consult a healthcare professional immediately. Moreover, prolonged use of this medication may lead to resistant bacteria, so it is important to check the sensitivity of the infectious bacteria and take it for the minimum required duration only. Interactions may occur when taken with other medications, particularly caution is needed when taken with probenecid, antacids, nephrotoxic drugs, anticoagulants, and oral contraceptives. For women who are pregnant or breastfeeding, if administration of this drug is necessary, benefits and risks should be thoroughly considered before making a decision. Safety for newborns and children, especially infants under 1 month, has not been established, so caution should be exercised in usage. Elderly patients may experience side effects more easily due to decreased bodily functions, so dosing and intervals should be adjusted and observed carefully. This drug may affect some clinical test results, so inform the healthcare provider of this drug use during testing. In the event of an overdose, symptoms such as nausea, vomiting, abdominal discomfort, diarrhea may appear, and it is important to seek appropriate treatment at a medical facility promptly.

Side effects and when to seek care immediately

Serious side effects

  • Shock
  • urticaria
  • edema
  • respiratory distress
  • angioedema
  • anaphylactic symptoms
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • agranulocytosis
  • pancytopenia
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  • aplastic anemia
  • hemolytic anemia
  • hepatitis
  • jaundice
  • acute renal failure
  • severe colitis
  • interstitial pneumonia
  • eosinophilic pulmonary infiltrates
  • seizures
  • confusion

Mild side effects

  • Generalized flushing
  • sensory disturbances
  • fainting
  • hypertension
  • vasodilation
  • rash
  • erythema
  • itching
  • fever
  • lymphadenopathy
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  • arthralgia
  • serum sickness-like reaction
  • thrombocytopenia
  • eosinophilia
  • lymphocytosis
  • leukopenia
  • aplastic anemia
  • hemolytic anemia
  • reversible neutropenia
  • increased AST
  • ALT
  • ALP
  • elevated BUN
  • increased serum creatinine
  • nausea
  • vomiting
  • diarrhea
  • abdominal pain
  • gastrointestinal discomfort
  • heartburn
  • loss of appetite

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container that blocks light and at a suitable room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness over time.

Appearance and packaging

Appearance

Upper part is blue opaque and lower part is white opaque hard capsule filled with light yellow powder

Package unit

30 capsules/bottle, 300 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.