Medication info
Esomeprazole Magnesium Hydrate 20 mg Tablet

Esomeprazole Magnesium Hydrate 20 mg Tablet

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Dihydrate›21.69mg / 1 tablet
Manufacturer / importer
(주)휴온스
Appearance
Pink oval film-coated tablets
Packaging
14 tablets (7 tablets/Alu-Alu x 2)
Approval status
Active

MFDS item code 201507272 · Approved 2015.10.21 · Insurance code 670607320

Summary

Main use
Treatment of gastroesophageal reflux disease (including erosive esophagitis) and eradication of Helicobacter pylori positive peptic ulcer, alleviation of gastrointestinal symptoms related to non-steroidal anti-inflammatory drugs.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment for erosive esophagitis: 40 mg once daily for 4 weeks; if symptoms persist, take for an additional 4 weeks. - Maintenance therapy for prevention of recurrence: 20 mg once daily. - Treatment for gastroesophageal reflux disease symptoms without esophagitis: 20 mg once daily.
Children's dosage
Adolescents aged 12 years and older: 1) Gastroesophageal reflux disease (GERD) - Treatment for erosive esophagitis: 40 mg once daily for 4 weeks; if symptoms persist, take for an additional 4 weeks. - In cases without esophagitis but with reflux symptoms: 20 mg once daily.

Ingredients

Manufacturer
(주)휴온스

Efficacy & effects

Treatment of gastroesophageal reflux disease (including erosive esophagitis) and eradication of Helicobacter pylori positive peptic ulcer, alleviation of gastrointestinal symptoms related to non-steroidal anti-inflammatory drugs.

  • Gastroesophageal reflux disease
  • erosive esophagitis
  • esophagitis
  • duodenal ulcers
  • peptic ulcers
  • upper gastrointestinal pain
  • upper gastrointestinal discomfort
  • upper gastrointestinal burning sensation
  • gastric ulcers
  • duodenal ulcers
  • Zollinger-Ellison syndrome
  • rebleeding.
View approved original text

This medication is used for the treatment of gastroesophageal reflux disease, especially for erosive esophagitis and long-term maintenance therapy for prevention of recurrence. It also helps alleviate symptoms of gastroesophageal reflux without esophagitis. This drug is used in combination with antibiotics for the treatment of duodenal ulcers caused by Helicobacter pylori infection and prevention of recurrent peptic ulcers. It is effective for treating and preventing gastric and duodenal ulcers associated with upper gastrointestinal symptoms due to NSAID use. Additionally, it is used for the treatment of Zollinger-Ellison syndrome and maintenance therapy for the prevention of rebleeding from gastric and duodenal ulcers. In summary, this medication is widely used for treating gastrointestinal and esophageal-related diseases and for preventing ulcers.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment for erosive esophagitis: 40 mg once daily for 4 weeks; if symptoms persist, take for an additional 4 weeks. - Maintenance therapy for prevention of recurrence: 20 mg once daily. - Treatment for gastroesophageal reflux disease symptoms without esophagitis: 20 mg once daily.

Children's dosage

Adolescents aged 12 years and older: 1) Gastroesophageal reflux disease (GERD) - Treatment for erosive esophagitis: 40 mg once daily for 4 weeks; if symptoms persist, take for an additional 4 weeks. - In cases without esophagitis but with reflux symptoms: 20 mg once daily.

Precautions

This medication should not be used in patients with allergies or hypersensitivity to certain ingredients. In particular, patients sensitive to benzimidazole derivatives, penicillin antibiotics, or macrolide antibiotics should not receive this medication. Patients taking certain heart-related medications or antivirals, nursing mothers, and patients with a history of myocardial infarction should not use this drug. This medication contains a dye called Yellow No. 5, and patients with a history of allergy to this component should use it with caution. Various side effects may occur when taking this medication, including headache, dizziness, abdominal pain, diarrhea, nausea, skin rash, and itching. If these symptoms are severe or persistent, consult healthcare professionals. Although rare, blood abnormalities, severe allergic reactions, liver dysfunction, and severe skin reactions may occur, so if abnormal symptoms arise, immediate medical care should be sought. This drug suppresses gastric acid, which may increase the risk of bacterial infections in the gastrointestinal tract, so if diarrhea persists for a long time, notify healthcare professionals. Long-term use may increase the risk of fractures; therefore, patients with osteoporosis should have regular bone density tests. Additionally, prolonged use may lower blood magnesium levels, so patients who take it long-term or are at risk for hypomagnesemia should be monitored through blood tests. This medication has a high potential for drug interactions, so patients taking anticoagulants, antiepileptics, certain antibiotics, or antivirals should inform their doctor. During pregnancy, this medication should be used cautiously as its safety for the fetus has not been fully established, and nursing mothers should avoid taking it. In case of overdose, there is no specific antidote; therefore, one should go to the hospital immediately for appropriate treatment and keep it out of reach of children to prevent accidents.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, anaphylactic reactions, shock, angioedema, rash, mucosal skin syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), jaundice, liver failure, encephalopathy, bronchospasm, difficulty breathing, dyspnea, severe allergic reactions, severe skin adverse reactions, severe swelling, or urinary difficulties.

Mild side effects

  • Leukopenia
  • thrombocytopenia
  • agranulocytosis
  • pancytopenia
  • fever
  • peripheral edema
  • hyponatremia
  • hypomagnesemia
  • insomnia
  • agitation
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  • mental confusion
  • depression
  • aggressiveness
  • hallucinations
  • headache
  • dizziness
  • sensory disturbances
  • drowsiness
  • dysgeusia
  • blurred vision
  • dizziness (labyrinthine)
  • bronchospasm
  • pancreatitis
  • abdominal pain
  • constipation
  • diarrhea
  • abdominal distension
  • nausea
  • vomiting
  • dry mouth
  • stomatitis
  • gastrointestinal candidiasis
  • microscopic colitis
  • liver enzyme elevation.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air and moisture from entering, and it is recommended to store it at room temperature between 1 and 30 degrees Celsius. Storing it in this manner will help maintain its effectiveness and prevent degradation.

Appearance and packaging

Appearance

Pink oval film-coated tablets

Package unit

14 tablets (7 tablets/Alu-Alu x 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.