Han-in Sertraline Tablets 50 mg (Sertraline Hydrochloride)

Adult dosage

Depression and obsessive-compulsive disorder: Administer 50 mg orally once daily as the initial dose. The maintenance dose is 50-100 mg daily, and if the effect is insufficient, it can be increased by 50 mg to a maximum of 200 mg daily. Panic disorder, post-traumatic stress disorder, and social anxiety disorder: Start with 25 mg once daily and increase to 50 mg after one week. Clinically, it can be administered within a range of 50-200 mg daily.

Children's dosage

Obsessive-compulsive disorder (ages 6-17): For children aged 6-12 years, start with 25 mg once daily; for those aged 13-17 years, start with 50 mg once daily. If there is no response, the dose can be increased up to a maximum of 200 mg daily.

This medication can increase the risk of suicidal thoughts or behaviors in young people with major depression or psychiatric disorders; therefore, it should be prescribed with caution by a physician. During treatment, patients or their guardians should monitor closely for signs of suicidal tendencies, aggression, or unstable behavior changes. There is a risk of a serious side effect known as serotonin syndrome, so caution must be exercised when taking this drug with other medications that affect serotonin. Particularly, it should not be taken with monoamine oxidase inhibitors (MAOIs) as this combination is dangerous. The drug should not be used in patients with severely impaired liver function, those who are hypersensitive to this medication, or patients taking certain medications. Patients with epilepsy may have a heightened risk of seizures, so caution is especially needed when administering this drug. Patients with mild liver impairment may require dosage adjustments or extended dosing intervals. This medication may affect mental and physical abilities, causing drowsiness or dizziness; therefore, caution should be exercised when driving or operating hazardous machinery. Pregnant women or those who may become pregnant should use this drug cautiously after consulting a physician as it may affect the fetus. Nursing mothers should also administer this drug under a physician's advice as it may partially pass into breast milk and affect the baby. If treatment is stopped abruptly, withdrawal symptoms such as dizziness, anxiety, and sleep disturbances may occur, so the dosage should be gradually reduced. There may be an increased risk of bleeding during treatment; therefore, caution is needed when taken with drugs that affect bleeding tendencies or blood coagulation. In cases of overdose, symptoms such as heart issues, drowsiness, vomiting, and tremors may appear, necessitating immediate medical attention. This medication should be kept out of the reach of children and not transferred to other containers.

Serious side effects

• Urticaria
• angioedema
• toxic epidermal necrolysis
• Stevens-Johnson syndrome
• purpura
• rash
• liver damage
• leukopenia
• thrombocytopenia
• hyponatremia

Mild side effects

• Decreased appetite
• increased appetite
• hypoglycemia
• hyperglycemia
• insomnia
• depressive symptoms
• decreased libido
• agitation
• anxiety
• hallucinations

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. Additionally, avoid storing it in extremely hot or cold places, and it is best to keep it at room temperature between 1°C and 30°C.

Appearance

White, oblong film-coated tablet

Package unit

For domestic use - 30 tablets/bottle, for domestic use - 100 tablets/bottle, for export - 30 tablets/box [(10 tablets/PTP x 3)]