Olostat 10/10 mg (Olmesartan Medoxomil, Rosuvastatin)

Adult dose

Olmesartan Medoxomil: Adults should take 10 mg once daily, regardless of meals. If blood pressure control is insufficient, it may be increased to 20 mg once daily, with a maximum dosage of 40 mg. Rosuvastatin: The initial dose is 5 mg once daily, and the maintenance dose may be adjusted to 10 mg once daily as needed. The maximum dose is 20 mg once daily. When taking, it is recommended to take it at the same time every day (for example, in the morning).

Child dose

Safety and efficacy in pediatric patients under 18 years of age have not been established.

This medication can cause serious harm or even death to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it must be discontinued immediately if pregnancy is confirmed. It should not be used by individuals with allergies to this medication or its components, pregnant women or women of childbearing age, nursing mothers, patients undergoing dialysis, patients with severe renal insufficiency, patients with severe liver impairment, patients with biliary obstruction, patients with unexplained liver dysfunction, and patients with muscle diseases. Particularly, high doses of rosuvastatin may pose a higher risk of muscle damage, so patients with reduced kidney function, hypothyroidism, or a history of genetic muscle disorders should be cautious. This medication contains lactose and should not be given to patients with lactose intolerance or related genetic disorders. When this medication is first administered to patients with reduced blood volume or salt, hypotensive symptoms may occur, so their condition should be closely monitored, and appropriate action should be taken if hypotension occurs. This medication may affect kidney function; therefore, patients with renal impairment or those who have had a kidney transplant should have their kidney function and electrolyte status regularly checked by blood tests. Due to the risk of hyperkalemia, especially in heart failure or renal impairment patients, blood potassium levels should be closely monitored. Particular care is required when using this medication on patients with aortic stenosis or obstructive heart disease. This medication may cause dizziness due to its blood pressure-lowering effects; therefore, caution is needed when operating machinery or performing high-risk tasks, such as driving. Patients with a history of liver disease or excessive alcohol intake should undergo regular liver function tests; if liver function abnormalities arise, treatment should be discontinued immediately. Muscle pain, myopathy, and rarely rhabdomyolysis may occur; therefore, patients should immediately report any occurrence of muscle pain, weakness, or cramps to their healthcare provider for necessary testing. This medication may interact with other drugs, so especially when taking potassium-sparing diuretics, lithium, non-steroidal anti-inflammatory drugs, and fibrates, it is essential to consult a specialist. Women who are pregnant or planning to become pregnant must strictly use proper contraceptive methods, and if pregnancy is confirmed, the medication should be discontinued immediately. Nursing mothers should either stop breastfeeding or discontinue this medication while taking it, and safety for pediatric patients and adolescents under 18 years of age has not been established. Elderly patients may have increased blood concentrations of this drug, thus requiring dosage adjustment and monitoring. In cases of overdose, symptoms such as hypotension, palpitations, and bradycardia may occur; appropriate treatment should be provided based on the symptoms. This medication should be kept out of reach of children, and it is advisable not to transfer it to another container. If any abnormal symptoms or discomfort occur during the use of this medication, it is crucial to consult a healthcare professional immediately to receive appropriate action.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, breathing abnormalities with cough and fever, yellowing of skin or eyes (jaundice), profound malaise, sudden and severe headache, lightning-like headache, seizures, confusion, visual disturbances, paralysis,

Mild side effects

• Headache
• dizziness
• decreased perception
• drowsiness
• gastroesophageal reflux
• constipation
• tooth decay
• dyspepsia
• gastric ulcer
• gastritis

This medication may be sensitive to air or moisture, therefore, it must be stored in a tightly sealed container. It is also important to keep it at room temperature between 1°C and 30°C to maintain the drug's efficacy.

Appearance

Light pink circular film-coated tablet

Package unit

30 tablets (10 tablets/PTP) x 3, 30 tablets/bottle