Cravast 10mg (Rosuvastatin Calcium)

Adult dosage

Initiate with 5 mg once daily, and if a greater reduction in LDL cholesterol is required, adjust to a maintenance dose of up to 10 mg once daily. The maintenance dose should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and the patient's response at intervals of 4 weeks or longer, with a maximum daily increase of up to 20 mg. The recommended initial dosage for Asian patients and those prone to myopathy is

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the dosage is administered once daily between 5 mg and 20 mg, with no clinical data available for dosages higher than 20 mg.

This medication should not be used in certain patients. For example, it should not be administered to patients who are allergic to any of the ingredients, those with severely compromised liver function, patients with muscle diseases, and those with severe kidney dysfunction. Additionally, it is not safe to use this medication in pregnant or breastfeeding women, and fertile women who do not use adequate contraception. When using this medication, regular checks of liver function and muscle condition are required. Especially for patients who consume large amounts of alcohol or have a history of liver disease, it is important to repeatedly confirm liver enzyme tests. Muscle pain or weakness symptoms should be promptly reported to medical staff, and the medication should be discontinued if necessary. This medication may increase the risk of muscle damage when used with certain drugs, so it is essential to inform a physician or pharmacist if taking other medications. Caution is especially needed when used in combination with fibrate-class medications, and high dosages should be avoided. This medication can affect the liver and kidneys, so regular liver function and kidney function tests are recommended during use. It may also increase blood sugar levels, requiring thorough blood sugar management in patients with diabetes or at risk for diabetes. Pregnant or breastfeeding individuals should avoid taking this medication, as it can pose risks to the fetus or infant, and women planning pregnancy should use appropriate contraception. In case of overdose, there are no specific antidotes, and management should be done symptomatically with liver and muscle tests. This medication may cause dizziness when driving or operating machinery, so caution is advised. Lastly, if severe rash or allergic reactions occur during the use of this medication, immediate discontinuation and consultation with medical staff are necessary.

Serious side effects

Allergic reactions including urticaria and angioedema, Stevens-Johnson syndrome, eosinophilia and systemic symptom drug reaction syndrome (DRESS), jaundice, hepatitis, severe muscle weakness, ocular myasthenia, polyneuropathy, peripheral neuropathy, immune-mediated necrotizing myopathy, rhabdomyolysis, acute kidney failure, oliguria, thrombocytopenia, increased serum creatinine, severe edema, liver failure, severe allergic reactions, severe skin rash

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication should be stored in a tightly closed container to prevent exposure to air or light. Additionally, keep the storage temperature between 1 degree and 30 degrees Celsius at room temperature. Proper storage can help maintain the medication's effectiveness over time.

Appearance

Pink round film-coated tablet

Package unit

28 tablets/box[(14 tablets/Alu-Alu) X 2]