Lipostore 10 mg (Rosuvastatin Calcium)

Adult dosage

The initial dose is 5 mg once daily, and for patients needing further LDL cholesterol reduction, the maintenance dose can be adjusted accordingly. Most patients are controlled at a maintenance dose of 10 mg once daily. The maintenance dose should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient response every 4 weeks or longer intervals, up to a maximum of 20 mg daily.

Children's dosage

The typical dosage range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 5 mg to 20 mg once daily. The dosing should be adjusted according to the recommended treatment goals for each individual patient.

This medication should not be used in certain patients. For example, individuals who are allergic to this medication, those with liver problems, or those with muscle disorders should not take this medication. Additionally, individuals with severely impaired kidney function, pregnant or breastfeeding women should not use this medication. Women of childbearing potential should only use this medication if they are highly unlikely to become pregnant and are fully aware of the risks to the fetus. Patients at high risk of muscle-related diseases should avoid high doses of this medication, and caution is necessary for patients with moderate to severe kidney impairment, hypothyroidism, family history of muscle disorders, alcoholics, Asians, or those taking certain other medications. This medication contains lactose, so individuals with lactose intolerance should not take it. Regular monitoring of liver function and muscle condition is necessary while on this medication, and individuals with a significant history of alcohol consumption or liver disease should be particularly cautious. If symptoms such as muscle pain, weakness, or cramps occur, consult a doctor immediately, and in severe cases, this medication may need to be discontinued. Moreover, the risk of muscle disorders may increase based on other medications taken concurrently, so it is essential to inform the doctor of any current medications. Pregnant or breastfeeding women should not take this medication, and women who may become pregnant should use appropriate contraceptive methods. In cases of overdose, since there is no specific antidote, treatment should be based on symptoms, and liver and muscle function tests should be performed. This medication does not significantly affect the ability to drive or operate machinery, but dizziness may occur, so caution is advised. This medication may show higher concentrations in Asians, thus dosage adjustment may be necessary.

Serious side effects

Urticaria, chest tightness, difficulty breathing, increased serum creatinine, severe muscle weakness, ophthalmoplegia, jaundice, severe rash, blisters, skin peeling, pain of mucous membranes in the mouth/eyes, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms, immune-mediated necrotizing myopathy, rhabdomyolysis, acute renal failure, edema, thrombocytopenia, severe allergic reactions, severe skin adverse reactions, respiratory problems

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• urticaria
• myalgia
• weakness

This medication should be stored in a tightly closed container to protect from air or moisture. The recommended storage temperature is room temperature between 1 to 30 degrees Celsius.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle