Liposto Tablet 5 mg (Rosuvastatin Calcium)

Adult dosage

The initial dose is 5 mg once daily, and for those requiring more LDL-cholesterol reduction, the maintenance dose can be adjusted accordingly. Most patients are adjusted to a maintenance dose of 10 mg once daily. The maintenance dose should be appropriately adjusted based on LDL-cholesterol levels, treatment goals, and the patient’s response, with a maximum increase up to 20 mg once daily after an interval of 4 weeks or more.

Children's dosage

The typical dosage range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 5 mg to 20 mg once daily. The dosage should be adjusted according to the recommended treatment goals for each individual patient.

This drug should not be used in certain patients. For example, it should not be administered to patients who are allergic to any of the ingredients, have severely impaired liver function, have muscle diseases, or are taking certain medications concurrently. Women who are pregnant or breastfeeding, as well as women of childbearing potential, must use appropriate contraceptive methods before taking this medication and must be fully aware of the risks to the fetus. Furthermore, the use of high doses of this drug is contraindicated in patients at high risk for muscle diseases. Since this drug contains lactose, patients with lactose intolerance or related genetic disorders should not take it. Patients with a history of excessive alcohol consumption or liver disease must have regular liver function tests while taking this drug, and those with conditions such as hypothyroidism or nephrotic syndrome should receive treatment first. If symptoms such as myalgia or myopathy occur, you should immediately inform your doctor, and in severe cases, the administration should be stopped. This drug may interact with certain medications, so if you are taking other medications, it is essential to inform your physician or pharmacist. It is safer not to use this drug during pregnancy or breastfeeding, and if taken during pregnancy, it should be discontinued immediately. In the case of overdose, there is no specific antidote, so treatment should be based on the symptoms, and liver function and muscle damage should be monitored. Lastly, dizziness may occur during the use of this medication, so caution is required when driving or operating machinery.

Serious side effects

Allergic reactions including urticaria and angioedema, rhabdomyolysis, immune-mediated necrotizing myopathy, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe muscle weakness, ocular myasthenia, thrombocytopenia, polyneuropathy, peripheral neuropathy, cough, dyspnea, edema, fatal and non-fatal liver failure, acute renal failure, oliguria, chest discomfort

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• hematuria
• diarrhea

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain storage temperatures between 1 to 30 degrees Celsius at room temperature. Proper storage can help maintain the drug's efficacy for a long time.

Appearance

Yellow circular film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle