Crejet Tablet 10/5 mg (Ezetimibe, Rosuvastatin)

Adult dose

This medication is administered once daily regardless of meals. The dosage range is 10/5 mg to 10/20 mg per day. An initial dose of 10/5 mg is recommended. For patients requiring more significant LDL cholesterol reduction, the dosage may be adjusted. After starting treatment or adjusting the dose, lipid levels should be checked at intervals of at least 4 weeks to adjust the dosage accordingly.

This medication may pose a risk of muscle problems, so any symptoms such as muscle pain, muscle cramps, or muscle weakness should be reported to a physician immediately. Serious myopathy or rhabdomyolysis may occur; therefore, if these symptoms are severe or CPK levels significantly increase, treatment should be discontinued. Patients with poor liver function or a history of liver disease should undergo regular liver function tests, and if liver enzyme levels rise significantly, administration should be stopped. This medication should also be used with caution in patients with impaired renal function, and it should not be administered in cases of severe renal impairment. Pregnant or potentially pregnant women and nursing mothers should not use this drug, and fertile women should use effective contraception during treatment. Individuals with alcohol dependence, liver abnormalities, elderly patients, and hypothyroid patients, who have a higher risk of muscle problems, should consult a physician before administration. There may be interactions with other drugs; therefore, if there are any other medications being taken, they should be disclosed, particularly avoiding combination with fibrate class drugs. This medication contains lactose, so patients with lactose intolerance should not take it. Caution is advised as dizziness and other symptoms may occur during driving or operating machinery. Regular blood tests, liver function tests, and muscle-related tests during treatment are important to check for abnormalities.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain of mucous membranes in mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination problems.

Mild side effects

• Headache
• dizziness
• dyspepsia
• elevated ALT
• edema
• myalgia
• dry mouth
• elevated liver enzymes
• abnormal liver function tests
• increased serum lactate dehydrogenase

This medication should be stored in a tightly closed container to avoid exposure to air and moisture, and it is best to keep it at temperatures between 1 and 30 degrees Celsius. Storing it in this manner will help maintain the medication's effectiveness for a long time.

Appearance

Pink, rectangular, film-coated tablet

Package unit

30 tablets (10 tablets/ PTP x 3), 30 tablets/bottle, 100 tablets/bottle