Medication info

Diasisita Tablet 50/500 mg

Prescription medicationApproval withdrawn
Ingredient · strength
Sitagliptin Phosphate Hydrate›Strength being verifiedMetformin Hydrochloride›Strength being verified
Manufacturer / importer
(주)에이프로젠바이오로직스
Appearance
Pink oval film-coated tablet
Packaging
28 tablets/PTP, 56 tablets/PTP
Approval status
Approval withdrawn

MFDS item code 201506650 · Approved 2015.09.21

This product's status changed to Approval withdrawn on 2023.08.23. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement of blood sugar control in type 2 diabetes
Who uses it
Adults
Adult dosage
The dosage of this medication is determined considering the patient's current treatment regimen, efficacy, and tolerability within the daily maximum recommended doses of sitagliptin 100 mg and metformin 2000 mg for each ingredient. Generally, it is taken twice a day with meals, and the dose is gradually increased to minimize gastrointestinal adverse reactions from metformin. 1. For patients not treated with metformin: The initial dose is

Ingredients

Manufacturer
(주)에이프로젠바이오로직스

Efficacy & effects

Improvement of blood sugar control in type 2 diabetes

  • Difficulty in blood sugar control for patients with type 2 diabetes
View approved original text

This medication is used as an adjunct to diet and exercise to improve blood sugar control in patients with type 2 diabetes. It is administered initially when there is no prior experience with diabetes medication treatment and blood sugar control is difficult with monotherapy. Additionally, it is used when sufficient effect is not achieved with monotherapy with either metformin or sitagliptin, or when substituting treatment with both drugs. This medication can also be taken in conjunction with metformin in cases where blood sugar control is difficult due to the combination therapy with sulfonylureas, or metformin and thiazolidinediones. It helps in blood sugar management when combined with insulin and metformin when blood sugar control is not sufficient. This medication is effective in improving blood sugar control by complementing various stages of treatment.

Dosage and Administration

Adult dosage

The dosage of this medication is determined considering the patient's current treatment regimen, efficacy, and tolerability within the daily maximum recommended doses of sitagliptin 100 mg and metformin 2000 mg for each ingredient. Generally, it is taken twice a day with meals, and the dose is gradually increased to minimize gastrointestinal adverse reactions from metformin. 1. For patients not treated with metformin: The initial dose is

Precautions

This medication consists of sitagliptin and metformin and is used for the treatment of diabetes. When taking this medication, there can be severe allergic reactions, so if symptoms such as skin rash, shortness of breath, or swelling of the face or neck occur, stop taking it immediately and consult a doctor. Additionally, this medication can rarely cause severe pancreatitis, so if sudden abdominal pain, vomiting, or nausea occurs, inform healthcare providers immediately. Patients with severely impaired heart or kidney function, those with acute infections or dehydration, those with severe liver disease, and women who are pregnant or breastfeeding should not take this medication. During treatment, regular monitoring of kidney function is necessary, and discontinuation of the drug is required if kidney function declines. A rare but life-threatening condition called lactic acidosis may occur, so if severe fatigue, muscle pain, shortness of breath, or abdominal pain appears, visit the hospital immediately. This medication carries a risk of hypoglycemia, so caution is required when skipping meals or engaging in vigorous exercise, and more attention should be paid to hypoglycemic symptoms when taken with other antihyperglycemic agents. Alcohol consumption may increase the risk of side effects, so it is advisable to avoid excessive drinking during treatment. If undergoing surgery or tests involving radiocontrast agents, inform healthcare providers of this medication beforehand, and temporarily discontinue the medication if necessary. During treatment with this medication, regular blood tests, kidney function tests, and vitamin B12 level checks are important for monitoring health status. Elderly patients should be managed more carefully as kidney function may decline, and dose adjustments may be necessary. The safety and efficacy of this medication have not been established in children and adolescents, so it should not be used in these populations. If blisters appear on the skin or severe joint pain occurs during treatment, consult a doctor immediately. There may be interactions with other drugs, so if taking other medications, be sure to inform healthcare providers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, anaphylaxis, Stevens-Johnson syndrome, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, acute pancreatitis, acute renal failure, shortness of breath, jaundice, generalized malaise, sudden and severe headache, seizure, confusion, visual disturbances, paralysis, severe swelling accompanied by increased blood pressure or urinary abnormalities, acute renal failure.

Mild side effects

Diarrhea, upper respiratory infection, headache, nausea, vomiting, abdominal pain, nasopharyngitis, constipation, muscle pain, limb pain, back pain, pruritus, thrombocytopenia, decreased appetite, itching, dizziness, hypoglycemia, severe joint pain accompanied by disability

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be kept in a sealed container to prevent air or moisture exposure, and it is best stored at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain its effectiveness and prevents deterioration.

Appearance and packaging

Appearance

Pink oval film-coated tablet

Package unit

28 tablets/PTP, 56 tablets/PTP

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.