Metarins 50/850 mg

Adult dose

This medication is typically taken twice daily with meals, gradually increasing the dose to minimize gastrointestinal side effects caused by metformin. 1. For patients who are not currently receiving metformin: - The initial dose is one tablet (50/500 mg) taken twice daily, which can be increased to 50/1000 mg. 2. For patients receiving metformin: - Recommended starting dose...

This medication is a combination drug containing sitagliptin and metformin hydrochloride used for diabetes treatment. First, the sitagliptin component may cause a rare but serious allergic reaction, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur within 3 months after administration, you should stop using it immediately and consult a doctor. Furthermore, acute pancreatitis may occur, so if symptoms such as abdominal pain, vomiting, or loss of appetite occur, you should inform your healthcare professional immediately. The metformin hydrochloride component may cause a rare serious side effect called lactic acidosis, which can be accompanied by symptoms such as muscle pain, difficulty breathing, fatigue, and abdominal pain. Patients with impaired kidney function, severe infections, dehydration, or heart failure should not take this medication, and its use should be suspended for a certain period before and after tests using iodine contrast agents. It is recommended not to use this medication in pregnant or breastfeeding women or in children under 18 years old as safety has not been established. During the use of this medication, regular kidney function and blood tests should be performed, and checking vitamin B12 levels periodically is recommended. Also, due to the risk of hypoglycemia, special caution should be taken in cases of irregular meals, excessive exercise, or concurrent use with other hypoglycemic agents or alcohol. Before and after surgery, the administration of this medication should be discontinued for a certain period, and it should be resumed only after the patient's condition stabilizes. Excessive consumption of alcohol during treatment should be avoided, and if new symptoms or adverse reactions occur during medication use, you should consult a doctor immediately. Lastly, this medication may require caution when driving or operating machinery, so you should be well aware of hypoglycemic symptoms.

Serious side effects

Hives, angioedema, anaphylaxis, rash, vasculitis, Stevens-Johnson syndrome and desquamative skin diseases, acute pancreatitis, acute renal failure, difficulty breathing, acute deterioration of kidney function, severe and debilitating arthralgia, bullous pemphigoid, rhabdomyolysis, severe rash with high fever, blisters, skin shedding, pain in oral/ocular mucosa, liver abnormalities (jaundice), severe lactic acidosis, hypoglycemia, acute or chronic metabolic acidosis.

Mild side effects

• Diarrhea
• upper respiratory infections
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a tightly closed container to avoid exposure to air or moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

Pink oval film-coated tablet

Package unit

28 tablets/box [(14 tablets/PTPX2)], 56 tablets/box [(14 tablets/PTPX4)]