Sitameron Tablets 50/1000 Milligrams

Adult dosage

This medication is generally taken twice daily with food, and the dosage is gradually increased to minimize gastrointestinal side effects associated with metformin. 1. Patients who are not currently being treated with metformin: This drug 50/500 mg should be taken twice a day, 1 tablet per dose; it can be increased to 50/1000 mg, taking 1 tablet twice daily. 2. Patients already receiving metformin:

This medication is composed of sitagliptin and metformin and is used for diabetes treatment. During the intake of this drug, severe allergic reactions may occur; therefore, if symptoms such as hives, rashes, difficulty breathing, or swelling of the face or neck occur, it is necessary to stop taking the medication immediately and consult a doctor. This medication can cause a serious side effect called pancreatitis, which is inflammation of the pancreas; thus, if symptoms such as abdominal pain, nausea, vomiting, or fever occur, it is crucial to visit a healthcare institution immediately. Patients with poor kidney function or acute heart disease, severe infections, or dehydration should not use this medication, especially those with reduced kidney function should avoid or stop administration. Patients with acute or chronic liver disease should also avoid taking this medication for safety, and if liver function abnormality symptoms arise, they should consult a physician immediately. Women who are pregnant, may become pregnant, or are breastfeeding should not take this medication. Regular monitoring of kidney function and blood tests is important while using this drug, including checking vitamin B12 levels. Excessive alcohol consumption, rapid weight loss, or nutritional imbalance increases the risk of serious side effects such as hypoglycemia or lactic acidosis, hence caution is advised. If surgery is planned, the intake of this medication should be discontinued 48 hours before the procedure, and it should be resumed only after confirming that kidney function is normal post-surgery. When used with other hypoglycemic agents or insulin, this medication may increase the risk of hypoglycemia, so it is essential to be aware of hypoglycemic symptoms and possibly adjust doses of other medications as needed. In case of overdose, immediate notification to healthcare personnel is required, and blood dialysis or other treatments may be necessary. If blisters develop on the skin or severe joint pain occurs during treatment, consult a physician immediately as these symptoms may necessitate discontinuation of the medication. Finally, during the intake of this medication, it is important to maintain a regular eating and exercise routine, and to monitor blood glucose and kidney function through regular examinations.

Serious side effects

• Hives, angioedema, anaphylaxis, Stevens-Johnson syndrome, severe allergic reactions
• Acute pancreatitis, fatal or non-fatal hemorrhagic pancreatitis
• Acute renal failure, worsening of kidney function
• Respiratory distress
• Severe and disabling arthralgia
• Bullous pemphigoid
• Thrombocytopenia
• Severe hypoglycemia
• Acute renal failure
• Respiratory distress

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infections
• nasopharyngitis
• headache
• hypoglycemia
• constipation
• myalgia

This medication should be stored in a tightly sealed container to prevent air exposure, at a temperature between 1 to 30 degrees Celsius. This provides optimal maintenance of the drug's effectiveness.

Appearance

Dark red oval film-coated tablets

Package unit

PTP - 28 tablets/box [(14 tablets/PTP*2)], PTP - 56 tablets/box [(14 tablets/PTP*4)]