Crestor 10mg (Rosuvastatin Calcium)

Adult dosage

Take once daily at any time of the day, regardless of meals. The initial dose is 5 milligrams once daily, and the maintenance dose is adjusted for greater LDL-cholesterol reduction as needed. The maintenance dose of 10 milligrams once daily is suitable for most patients. The maintenance dose should be appropriately adjusted based on LDL-cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more.

Children's dosage

For pediatric patients aged 10 to 17 with heterozygous familial hypercholesterolemia, administer 5 milligrams to 20 milligrams once daily. The dosage should be individually adjusted based on treatment goals, and at intervals of 4 weeks or more.

This drug should not be administered to certain patients. For example, individuals who are allergic to this medication, those with active liver disease, muscle disorders, or severe renal impairment should not take this drug. Women who are pregnant, breastfeeding, or who may become pregnant should consult a specialist before use and employ appropriate contraception. Additionally, patients at high risk for myopathy or rhabdomyolysis should avoid high-dose therapy, and careful diagnosis and monitoring are needed before use for those with these risk factors. This medication contains lactose and should not be administered to patients with lactose intolerance or related genetic disorders. Patients who consume excessive alcohol or have a history of liver disease should have regular liver function tests, and those with hypothyroidism or nephrotic syndrome should prioritize treatment of the underlying condition. If symptoms such as muscle pain, weakness, fatigue, or fever occur, immediate medical consultation is necessary, and blood tests should be performed to check for muscle damage. This medication may interact with other drugs, especially with certain antivirals, immunosuppressants, and fibrates, so caution is required when used together. Clinical trials and post-market reports indicate that this drug can cause side effects such as liver function abnormalities, muscle-related adverse reactions, gastrointestinal disturbances, and skin rashes, so any abnormalities should be discussed with medical personnel. Avoid using this medication during pregnancy and breastfeeding, and women planning to become pregnant should ensure adequate contraception. There is no specific antidote for overdose, therefore treatment should be symptomatic, and liver function and muscle enzyme levels should be monitored. Dizziness may occur while taking this medication, so caution is required when driving or operating machinery.

Serious side effects

Allergic reactions including urticaria and angioedema, chest tightness, shortness of breath, jaundice, acute renal failure, oliguria, thrombocytopenia, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), severe muscle weakness, rhabdomyolysis, immune-mediated necrotizing myopathy, severe skin reactions, severe edema

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius. This helps to maintain the drug's effectiveness over time.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle