Solferak Tablet 10 mg (Solifenacin Succinate)

Adult dose

The recommended dose for adults (including the elderly) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This medication may be taken with or without food and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment No dosage adjustment is necessary for patients with mild or moderate renal impairment (creatinine clearance>30ml/min). For patients with severe renal impairment (creatinine clearance≤30ml/min), administer with caution and do not exceed 5mg once daily. 2. Patients with hepatic impairment No dosage adjustment is necessary for patients with mild hepatic impairment. For patients with moderate hepatic impairment (Child-Pugh class B), administer with caution and do not exceed 5mg once daily. 3. Patients receiving a strong cytochrome P450 3A4 (CYP3A4) inhibitor For patients receiving ketoconazole or another strong CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This drug should not be used in patients with urinary retention symptoms. Patients with serious gastrointestinal diseases such as toxic megacolon should also avoid this medication. It is also not safe for patients with myasthenia gravis or angle-closure glaucoma. Avoid this drug if you are allergic to it or any of its components. Patients undergoing hemodialysis or with severe liver or kidney dysfunction should not use this drug. Furthermore, patients with lactose intolerance or certain genetic metabolic disorders are advised against using this medication. Use with caution in patients at risk of urinary retention or with gastrointestinal obstructive diseases, or those at risk of decreased gastrointestinal motility. Patients with severe kidney impairment or decreased liver function should use with restricted dosage, and those taking strong CYP3A4 inhibitors should also be cautious. Patients with gastroesophageal reflux disease or autonomic neuropathy should be careful when using this medication. The most common side effects of this medication include dry mouth and constipation. Blurred vision or dry eyes may occur, and rarely, serious side effects such as urinary retention or bowel obstruction have been reported. If side effects occur, it is important to consult a doctor regarding discontinuation of the medication. This drug can cause severe allergic reactions such as cardiac arrhythmias, angioedema, or anaphylaxis, and if these symptoms appear, it should be discontinued immediately and you should seek treatment. Additionally, prior to taking this medication, other causes of urinary frequency or urinary tract infections should be evaluated. Caution should be exercised when taking this drug with other anticholinergic medications as effects may be enhanced or side effects may worsen. The effectiveness may be reduced when used with drugs that promote gastrointestinal motility. Since this medication is metabolized in the liver, there may be interactions with drugs that inhibit or induce certain liver enzymes, so you must inform your doctor about your current medications. The safety of this drug in pregnant women has not been established, so it should be used cautiously during pregnancy. During breastfeeding, it is advisable to avoid use as this drug may be secreted into breast milk. The safety and efficacy in pediatric patients have not been confirmed, so it should not be used in this population. In cases of overdose, symptoms such as headache, dizziness, drowsiness, and blurred vision may occur, and appropriate emergency measures such as gastric lavage or administration of activated charcoal may be necessary. Severe central nervous system symptoms, heart problems, or urinary retention may require professional treatment. This medication may require caution when driving or operating machinery due to drowsiness or blurred vision, so be mindful of symptoms.

• dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colonic obstruction
• intestinal obstruction
• angioedema
• nausea

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is recommended to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication.

Appearance

Bright pink round film-coated tablet

Package unit

100 tablets (10 tablets/PTP x 10), 30 tablets/bottle, 100 tablets/bottle