Glipril Tablet 4 mg (Glimepiride)

Adult dose

Adjusted individually for each patient. Taken without chewing with more than half a cup of water. Administered orally once a day. Must be taken before breakfast or right before the first meal. For initial monotherapy, the starting dose is 1 mg of glimepiride once a day, with subsequent increases of 1 mg at intervals of 1 to 2 weeks. Generally, additional effects are minimal when the dose exceeds 4 mg, but it can be increased to 6 mg if necessary.

This drug should not be used in patients with insulin-dependent diabetes or severe liver or kidney dysfunction. It is also advisable not to administer this drug to women who are pregnant or breastfeeding. Patients with severe infections, conditions around surgeries, or severe trauma should also avoid this medication, and it is preferable to switch to insulin therapy. This medication contains lactose, so patients with lactose intolerance or specific genetic metabolic disorders should not take it. At the beginning of treatment, there is a high risk of hypoglycemia, so patients with irregular eating habits, malnutrition, excessive exercise, or alcohol consumption should be especially cautious. Elderly patients, those with impaired liver or kidney functions, and those taking other medications should use this drug carefully under medical supervision due to the risks of hypoglycemia or drug interactions. Symptoms of hypoglycemia can include headache, severe hunger, nausea, fatigue, confusion, vision disturbances, dizziness, loss of strength, loss of self-control, temporary mental confusion, drowsiness, shallow breathing, bradycardia, sweating, cold and clammy skin, tachycardia, hypertension, palpitations, angina, arrhythmias, and blurred vision, so if any of these symptoms occur, immediate intake of sugar and consultation with a physician is necessary. During the use of this medication, it is important to maintain regular meals and exercise therapy, and to monitor blood sugar levels regularly to maintain proper blood sugar control. In case of overdose, contact medical personnel immediately for proper emergency treatment, as hypoglycemic coma may occur, requiring attention. The safety and efficacy of this drug in children has not been established, so it is preferable not to use it in individuals under 18 years of age. When storing, keep out of reach of children, and store tightly sealed in the original container.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, jaundice, abnormal liver function, hepatitis, thrombocytopenia, leukopenia, hemolytic anemia, anemia, agranulocytosis, pancytopenia, thrombocytopenic purpura, anaphylaxis, angioedema, skin and mucosal syndrome (Stevens-Johnson syndrome), allergic vasculitis, photosensitive skin reactions, decreased serum sodium concentration, severe headache, cerebral convulsions, coma.

Mild side effects

• Symptoms of hypoglycemia: headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• decreased agility or energy

This drug must be stored in a tightly sealed container to prevent air or moisture from entering. It is important to maintain storage temperatures between 1 degree and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness for a longer period.

Appearance

Light blue rectangular tablet

Package unit

30 tablets/bottle, 100 tablets/bottle