Solipro 5 mg (Solfenacin Succinate)

Adult dose

The usual recommended dose for adults (including older adults) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken with or without food and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment No dosage adjustment is required for patients with mild or moderate renal impairment (creatinine clearance>30ml/min). Use with caution in patients with severe renal impairment (creatinine clearance≤30ml/min), and do not exceed 5mg once daily. 2. Patients with hepatic impairment No dosage adjustment is required for patients with mild hepatic impairment. Use with caution in patients with moderate hepatic impairment (Child-Pugh class B), and do not exceed 5mg once daily. 3. Patients taking potent cytochrome P450 3A4 (CYP3A4) inhibitors For patients taking ketoconazole or another potent CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication should not be used in individuals with urinary retention symptoms. Additionally, it should not be administered to patients with severe gastrointestinal problems, myasthenia gravis, or certain glaucoma patients. Individuals with hypersensitivity to this medication or who are undergoing hemodialysis, as well as those with severe liver or kidney dysfunction, should also avoid using this medication. This medication contains lactose, so those with lactose intolerance or related genetic disorders should not take it. Caution should be exercised when administering this medication to individuals with a risk of urinary blockage or gastrointestinal obstructive diseases. Patients with moderate to severe impairment of kidney and liver function should also be carefully dosed with restrictions. Particularly, caution is required when taken with certain medications due to potential interactions. Taking this medication may cause side effects such as dry mouth, constipation, and blurred vision. Higher doses may increase the frequency of these symptoms, making dosage adjustment important. In severe cases, gastrointestinal issues such as bowel obstruction may arise, so immediate consultation with healthcare professionals is necessary if unusual symptoms occur. This medication can cause serious allergic reactions such as irregular heartbeat, vascular angioedema, and anaphylaxis, requiring immediate cessation of use and medical treatment if such symptoms occur. Caution is also needed when driving or operating machinery due to risks of drowsiness or blurred vision. Taking this medication along with other anticholinergic drugs can enhance its effects or worsen side effects. Moreover, it may reduce the effectiveness of medications that increase gastrointestinal motility, so consultation with professionals is advised. The safety of this medication has not been established for pregnant women, so caution is needed during usage, and breastfeeding women are advised to avoid it due to potential effects on infants. Safety and efficacy have not been confirmed for children, so it should not be used in this population. Overdose may cause symptoms such as headache, dizziness, drowsiness, and blurred vision; in severe cases, proper medical treatment at healthcare facilities may be necessary. This medication is reported to have no genetic toxicity or tumorigenic risk, and no special effects on reproductive ability or fetal development have been observed.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• nausea
• indigestion
• upper abdominal pain
• vomiting
• urinary tract infection

Store this medication in a tightly sealed container as it is sensitive to air and moisture. It is recommended to keep the storage temperature between 1°C and 30°C.

Appearance

Light pink round film-coated tablet

Package unit

100 tablets (10 tablets/PTP x 10)