Utrogestan Soft Capsules (Progesterone (Micronized))

Adult dose

Usually, 200 ～ 300 mg per day of micronized progesterone is administered orally in 2 divided doses: 100 mg in the morning and 100 ～ 200 mg at bedtime. Disorders due to progesterone deficiency: Administer 200 ～ 300 mg per day for 10 days, from day 17 to day 26 of each menstrual cycle (the first day of menstruation = day 1 of the menstrual cycle). Adjunct to estrogen therapy after menopause: Administer 200 mg per day for the last 2 weeks of each estrogen therapy cycle or for 10 ～ 12 days each month.

This medication should not be administered to certain patients. For example, those with an allergy to this drug, patients with kidney disease, patients who have previously experienced missed miscarriage or incomplete miscarriage, patients with or suspected of having breast cancer, patients with unexplained genital bleeding, patients with a history of thrombosis, patients with severe liver dysfunction, patients with a history of liver tumors, patients suspected of having estrogen-dependent malignancies, patients with cholestatic jaundice or certain liver diseases, and women who are pregnant or may become pregnant and nursing mothers should not use it. In addition, patients with hypertension, asthma, migraines, epilepsy, a history of heart or kidney disease, a history of depression, diabetic patients, and patients with a history of hormonal influence diseases should be cautious when using this medication. Taking this medication may cause changes in genital bleeding, breast pain, skin rash, liver dysfunction symptoms, neurological symptoms (depression, headache, dizziness), gastrointestinal issues (nausea, vomiting, diarrhea), thrombosis, and increased blood pressure, visual and auditory disturbances, swelling, and weight changes. Before using this medication, a breast and pelvic examination should be conducted, and regular examinations are necessary during treatment. If sudden changes in vision or migraines occur, discontinue use immediately, and caution is advised when driving or operating machinery due to possible drowsiness or dizziness. This medication may delay early natural miscarriage, so it should be used with caution, and it has no contraceptive effect. Additionally, there have been reports of an increased risk of liver tumors or breast cancer, so liver and breast conditions should be carefully monitored. Certain medications taken with this one may reduce or increase its effectiveness, so if you are taking other medications, always consult your physician or pharmacist. Smoking and alcohol can also affect the bioavailability of this medication. This medication should not be used during pregnancy, and it is essential to confirm whether one is pregnant before treatment. Nursing mothers are advised to avoid this medication. In cases of overdose, symptoms such as nausea, vomiting, drowsiness, and dizziness may occur, and treatment can be received to alleviate these symptoms as needed.

Destructive bleeding, spotting, changes in menstrual volume, amenorrhea, cervical erosion, changes in cervical discharge, shortened menstrual cycle, mid-cycle bleeding, histological changes in ovaries and uterus, breast tension, breast pain, liver spots, hyperpigmentation, allergic rash with or without itching, urticaria, acne, cholestatic jaundice, liver enlargement, depression, headache, drowsiness, dizziness, nausea, vomiting, diarrhea, constipation, thrombosis, cerebrovascular disorder, acute thromboembolism, sudden severe increase in blood pressure, visual impairment, hearing impairment, edema, increase or decrease in weight, temporary increase in sodium and chloride secretion

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, away from direct sunlight, and kept at room temperature. Storing it this way helps maintain the medication's effectiveness for a longer period.

Appearance

White to off-white spherical soft capsules filled with a homogeneous white emulsion

Package unit

30 capsules/PTP (15 capsules/PTP package x 2)