Medication info
CantaKan Plus Tablets 16/12.5 mg

CantaKan Plus Tablets 16/12.5 mg

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
(주)셀트리온제약
Appearance
Light orange, double convex, oval-shaped tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201504333 · Approved 2015.07.01 · Insurance code 693901660

Summary

Main use
Improvement of essential hypertension
Who takes it
Adults
Adult dose
The recommended dosage for this medication is 1 tablet once daily, taken regardless of meals. In adults, dosage adjustment of candesartan cilexetil should be considered before administration and can be directly transitioned from monotherapy when clinically appropriate. Antihypertensive effects are typically observed within 4 weeks of starting the treatment. No dosage adjustment is required for the elderly. Caution is advised in patients with decreased intravascular effective blood volume, including those with renal impairment or liver disease, when starting candesartan cilexetil.

Ingredients

Manufacturer
(주)셀트리온제약

Efficacy & effects

Improvement of essential hypertension

  • Essential hypertension
View approved original text

Essential hypertension is primarily treated with medications aimed at controlling blood pressure, especially when monotherapy proves inadequate. This medication acts through multiple components to more effectively lower blood pressure, assisting in its management. Therefore, it is suitable for patients with hypertension that cannot be controlled by individual components alone. This medication helps stabilize blood pressure management and contributes to preventing complications. Patients should maintain regular intake and monitor blood pressure regularly. It is used for the treatment of essential hypertension.

How to take

Adult dose

The recommended dosage for this medication is 1 tablet once daily, taken regardless of meals. In adults, dosage adjustment of candesartan cilexetil should be considered before administration and can be directly transitioned from monotherapy when clinically appropriate. Antihypertensive effects are typically observed within 4 weeks of starting the treatment. No dosage adjustment is required for the elderly. Caution is advised in patients with decreased intravascular effective blood volume, including those with renal impairment or liver disease, when starting candesartan cilexetil.

Precautions

This medication can cause serious harm to the fetus and newborn if taken during pregnancy, particularly in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. Individuals allergic to this medication or sulfonamide derivatives, pregnant or planning to become pregnant women, breastfeeding individuals, and those with severe kidney or liver disease should not use it. Patients with a history of angioedema, gout, hyponatremia, hypokalemia, hypercalcemia, or Addison's disease should also avoid this medication. Patients with reduced blood volume, sodium deficiency, liver disease, heart valve disease, hyperkalemia, decreased kidney function, and the elderly should use this medication carefully. Since it contains hydrochlorothiazide, there may be an increased risk of skin cancer; thus, caution is needed when exposed to sunlight, and regular skin condition monitoring is required. While taking this medication, side effects such as headache, dizziness, fatigue, dyspepsia, urinary tract infections, etc., may occur, and rarely blood abnormalities, liver function abnormalities, or allergic reactions may arise. Kidney function or electrolyte levels should be checked periodically, paying particular attention to potassium, sodium, and magnesium levels. If taken with other antihypertensives, diuretics, potassium supplements, NSAIDs, etc., interactions may occur and increase the risk of side effects; therefore, a consultation with healthcare professionals is essential. Pregnant or breastfeeding women should not use this medication, and particularly those breastfeeding should consider discontinuation for safety. Safety in pediatric patients and teenagers under 18 years of age has not been established, thus it is advisable not to use it. In case of overdose, symptoms such as hypotension, dizziness, electrolyte imbalance may appear, and immediate medical attention should be sought. This medication should be stored out of the reach of children and kept in its original packaging to prevent misuse or degradation in quality. Caution is needed during activities that require alertness, such as driving or operating machinery, as dizziness or lethargy may occur.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in oral or ocular mucous membranes, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough and fever, breathing issues, yellowing of skin or eyes (jaundice), generalized lethargy, liver abnormalities (jaundice), sudden and severe symptoms.

Mild side effects

  • Headache
  • back pain
  • dizziness
  • respiratory infections
  • symptoms similar to the common cold
  • sinusitis
  • bronchitis
  • urinary tract infections
  • nausea
  • bruising
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  • tachycardia
  • fatigue
  • abdominal pain
  • pharyngitis
  • dyslipidemia
  • nasopharyngitis
  • cough
  • elevated blood sugar
  • increased serum uric acid
  • elevated ALT
  • increased AST
  • elevated creatinine
  • increased urea
  • increased potassium
  • decreased sodium
  • leukopenia
  • neutropenia
  • agranulocytosis
  • dizziness
  • intestinal vascular symptoms.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture, ideally at room temperature between 1°C and 30°C. Proper storage helps maintain the medication's effectiveness.

Appearance and packaging

Appearance

Light orange, double convex, oval-shaped tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.