Medication info

Biforn Eye Drops 0.05% (Cyclosporine) (Single Use)

Prescription medicationApproval revoked
Ingredient · strength
Cyclosporine›Strength being verified
Manufacturer / importer
Hwa-il Pharmaceutical Co., Ltd.
Appearance
A white, opaque or slightly translucent homogeneous liquid contained in a white translucent plastic bottle.
Packaging
0.4ml/vial × 10, 0.4ml/vial × 30,
Approval status
Approval revoked

MFDS item code 201504245 · Notified 2015.06.30

This product's status changed to Approval revoked on 2023.06.28. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement of suppressed tear production due to ocular inflammation associated with keratoconjunctivitis sicca
Who uses it
Adults
Adult dosage
Instill 1 drop of this drug into each eye twice daily, approximately 12 hours apart. Before use, invert the container several times to mix until the suspension is uniformly opaque and white. If this drug is used with artificial tears, administer them 15 minutes apart. Discard any remaining solution and the container after instillation.

Ingredients

Manufacturer
Hwa-il Pharmaceutical Co., Ltd.

Efficacy & effects

Improvement of suppressed tear production due to ocular inflammation associated with keratoconjunctivitis sicca

  • Inhibited tear production
  • dry corneal conjunctivitis
  • inflammatory eye disease
View approved original text

This medication helps to increase tear production in patients who have suppressed tear secretion, alleviating symptoms associated with dry corneal conjunctivitis. It reduces dryness and discomfort in the eyes, and is used to improve eye health.

Dosage and Administration

Adult dosage

Instill 1 drop of this drug into each eye twice daily, approximately 12 hours apart. Before use, invert the container several times to mix until the suspension is uniformly opaque and white. If this drug is used with artificial tears, administer them 15 minutes apart. Discard any remaining solution and the container after instillation.

Precautions

This drug has not been sufficiently studied in patients with a history of herpetic keratitis, so caution is advised for use. The effect of increased tear production has not been observed in patients using local anti-inflammatory drugs or tear plugs. This medication should not be used in patients with active eye infections or known or suspected hypersensitivity to any component of this drug. Adverse reactions may include burning in the eyes, conjunctival hyperemia, discharge, eye pain, foreign body sensation, and itching; rarely, severe allergic reactions such as angioedema or difficulty breathing may occur. When using this medication, care should be taken to avoid the tip of the container touching the eye or any other surfaces to prevent contamination, and temporary blurred vision may occur after instillation, so it is advisable to avoid driving or operating dangerous machinery until vision returns to clarity. The safety of this drug during pregnancy has not been established; it should be used cautiously and only when necessary, and similar caution is needed for breastfeeding. The safety and efficacy of this medication have not been adequately established in children under 16 years of age. Opened containers should be used only once, and any remaining medication should be discarded, ensuring that the tip does not touch the eye or any other surface to prevent contamination. Do not use this medication while wearing contact lenses; lenses should be removed before instillation and can be reinserted 15 minutes after application. This medication should be kept out of reach of children, and expired drugs should be discarded.

Side effects

  • burning sensation in the eyes
  • conjunctival hyperemia
  • discharge
  • epiphora
  • eye pain
  • foreign body sensation
  • itching
  • pain in the eye
  • visual disturbance
  • eye swelling
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  • hypersensitivity reaction
  • severe angioedema
  • facial swelling
  • tongue swelling
  • pharyngeal edema
  • difficulty breathing
  • ocular surface damage
  • pruritus
  • hives
  • dry eyes
  • eyeache
  • abnormal sensations in the eyes
  • eye fatigue
  • eye irritation
  • corneal erosion
  • sticky eyes
  • eyelid edema

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 15 and 25 degrees Celsius at room temperature to safely preserve the drug's efficacy.

Appearance and packaging

Appearance

A white, opaque or slightly translucent homogeneous liquid contained in a white translucent plastic bottle.

Package unit

0.4ml/vial × 10, 0.4ml/vial × 30,

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.